02-Ateroskleros

Question 1

(02) Lennart N (1/20)
Arteroskleros? ASCVD?

Answer 1

(INTIMAFÖRTJOCKNING)
(ACS) (CCS) (CVA) (PAD)
(AS) (SUBKLINISK ASCVD)

Question 2

(02) Lennart N (2/20)
Response to retention?

Answer 2

(EN-DYSF) (INT HYPERP)
(LDL RET) (OxLDL/MoLDL)
(MAKROF) (IMM) (PLACKP)

Question 3

(02) Lennart N (3/20)
Riskfakt? Shear stress?

Answer 3

(BIFURKATIONER)
(INRE KURVATUR)
(OSCILLATORISK)

Question 4

(02) Lennart N (4/20)
Endoteldysfunktion?

Answer 4

(VASOK) -(VASOD)
(ROS/RNS) (PROINFL)
(MEDIA:SMC) (PROTROM)

Question 5

(02) Lennart N (5/20)
Retention lipoproteiner?

Answer 5

(INFLUX) (<70 nm)
(EFFLUX) (ApoB) (EJ HDL)
(RET:ART:PG:GAG-ApoB)

Question 6

(02) Lennart N (6/20)
Varför mycket oxLDL?

Answer 6

(RETENT) (OXIDAT)
-(IgM) -(Treg) (M1-M)
-(EFF-CYT) -(CHO-REF)

Question 7

(02) Lennart N (7/20)
Makrofaginfiltration?

Answer 7

(M1-M:TNF-A/IL6/IL12)
(MOX/M4) (MHB/Mhem)
(M2-M:IL10/IL4) (ANTI)

Question 8

(02) Lennart N (8/20)
Makrofag-foamceller?

Answer 8

(LDLR) (A-LDL) (OxLDL)
(A-LDLR) (SR-A) (CD36)
(LDL:INTIMA XANTOM)

Question 9

(02) Lennart N (9/20)
MoLDL? OxLDL? T-celler?

Answer 9

(T-bet:Th1:INF-Y/TNF-A)
(TF) (GATA3:Th2:IL4/IL5)
(FoxP3:Treg:TGF-B/IL10)

Question 10

(02) Lennart N (10/20)
T-regulatoriska celler?

Answer 10

(4-5% PERIFERA CD4+)
-(Th1) -(IFN-Y) (M2-M)
(EFFEROCYTOS) (REGR)

Question 11

(02) Lennart N (11/20)
Plackprogression?

Answer 11

(PRO) (ANTI)
(M1-M) (APO/NEK) (NEOV)
(M2-M) (EFFERO) (EFFLUX)

Question 12

(02) Lennart N (12/20)
Efferocytos?

Answer 12

(M2-M) (SCAVENGER)
-(SEK NEK) (TGF-B/IL10)
-(NEKROTISK KÄRNA)

Question 13

(02) Lennart N (13/20)
Defekt efferocytos?

Answer 13

(M1-M) (OxLDL) -(EAT ME)
(SEK NEK) (TNF-A/IL1B)
(NEKROTISK KÄRNA)

Question 14

(02) Lennart N (14/20)
Stabila vs instabila?

Answer 14

(FIBRÖS KAPPA)
(KOLLAGEN) (SMC)
(STABILITET) (TJOCKLEK)

Question 15

(02) Lennart N (15/20)
Trombos? Plackruptur?

Answer 15

(TCFA) (MMPs) (LIPIDK)
(TROMBOCYTAGGREG)
(FIBRIN/ERYTROCYTER)

Question 16

(02) Lennart N (16/20)
Trombos? Plackerosion?

Answer 16

(MMPs) (ENDOT) (EXPON)
(NEU-TROMBO-KOMPLEX)
(NETs) (E-C TRÅDAR) (VIT)

Question 17

(02) Lennart N (17/20)
ASCVD behandling?

Answer 17

(MULT) (KVAN) (KUMU)
(PREVENTIV PARADOX)
(LIVS) (MEDICIN) (REVAS)

Question 18

(02) Lennart N (18/20)
Livsstilsintervention?

Answer 18

(OFTA PÅ FLERA OLIKA M)
(MYCKET FÖRDELAKTIGT)
(SÄKRA) (KOSTNADSEFFE)

Question 19

(02) Lennart N (19/20)
Omega-3? EPA? DHA?

Answer 19

-(ED) -(INFLA) -(TAG)
-(TROMBOXANER)
(PROSTACYKLINER)

Question 20

(02) Lennart N (20/20)
ASCVD läkemedel?

Answer 20

(LLT) (HTN T)
(DM T/T2DM T)
(AAT) (APAs) (AC)