012915 pearls Flashcards

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1
Q

compare thyroid and steroid half lives

A

thyroid hormones are bound over 99.5% to TBG, transthyretin, and albumin. so their plasma half life is very long

steroid hormones-bound 90-98% to plasma proteins. half lives are shorter than thyroid hormones

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2
Q

what is responsible for the neurological symptoms and signs seen in the various sodium disorders (DI, SIADH)?

A

water movement from different osmolalities

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3
Q

what is the major factor in controlling AVP release?

A

plasma osmolality (arterial pressures falls of over 10% will lead to exponential increase in AVP release, but under this percentage, AVP release is not as sensitive to arterial pressures as it is to osmolality)

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