012915 pearls Flashcards
1
Q
compare thyroid and steroid half lives
A
thyroid hormones are bound over 99.5% to TBG, transthyretin, and albumin. so their plasma half life is very long
steroid hormones-bound 90-98% to plasma proteins. half lives are shorter than thyroid hormones
2
Q
what is responsible for the neurological symptoms and signs seen in the various sodium disorders (DI, SIADH)?
A
water movement from different osmolalities
3
Q
what is the major factor in controlling AVP release?
A
plasma osmolality (arterial pressures falls of over 10% will lead to exponential increase in AVP release, but under this percentage, AVP release is not as sensitive to arterial pressures as it is to osmolality)