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Gastrointes 2 > 011415 pancreatic malignancies > Flashcards

011415 pancreatic malignancies Flashcards

1
Q

most common pancreatic cancer

A

ductal adenocarcinoma

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2
Q

painless jaundice

A

exocrine pancreatic cancer

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3
Q

role of carbonic anhydrase in diagnosing pancreatic cancer

A

often normal in early stages so not useful for screening purposes

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4
Q

tx of pancreatic cancer

A

80-85% of pancreatic cancers are unresectable at time of diagnosis b/c of distant metastases (liver) or invasion of major blood vessels

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5
Q

prognosis for pancreatic ductal adenocarcinoma

A

poor

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6
Q

pancreatic cystic neoplasms-what types are there?

A

mucinous neoplasms

  • –mucinous cystic neoplasm
  • –intraductal papillary mucinous neoplasm

non-mucinous neoplasms
—serous cystadenoma

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7
Q

what is a mucinous cystic neoplasm

A

ovarian like stroma that secretes mucin

no communication w/ pancreatic duct

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8
Q

is mucinous cystic neoplasm benign or malignant?

A

benign, but has risk of malignancy so it’s surgically resected

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9
Q

intraductal papillary mucinous neoplasm is

A

mucin-producing papillary neoplasm of the PANCREATIC DUCT

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10
Q

types of IPMN

A

main duct IPMN
branch duct IPMN
mixed type IPMN

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11
Q

management of IPMN

A

main duct-surgical resection due to risk of malignancy

side branch-lower risk of malignancy so safe to monitor if small and no pancreatitis

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12
Q

serous cystadenoma

A

no communication w/ pancreatic duct

lined by glycogen rich cells originating from pancreatic acinar cells

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13
Q

management of serous cystadenoma

A

leave it alone (malignant possibility very rare)–like focal nodular hyperplasia (also like focal nodular hyperplasia b/c has the central scar stellate appearance)

exception is when it’s symptomatic

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14
Q

US is good or not good for the pancreas

A

not good

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15
Q

best way to diagnose small pancreatic lesions

A

endoscopic ultrasound

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16
Q

pancreatic neuroendocrine tumors-ex

A 
gastrinomas
insulinomas (most common)
somatostatinomas
glucagonomas
VIPomas
17
Q

why can somatostatinoma lead to steatorrhea

A

because inhibits secretin so that pancreatic enzymes can’t work in acidic pH

Gastrointes 2 (15 decks)

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