011315 viral hepatitis Flashcards
clinical manifestations of acute viral hepatitis
fever, malaise, anorexia, nausea, vomiting, jaundice, abdominal/RUQ pain, hepatomegaly
is there inflammation in chronic hepatitis?
no (only in acute)
what is the one test for diagnosing hep A?
Hep A antibody
what does Hep A IgG suggest?
previous exposure (more than 6 months out) and now immune or vaccination
does getting hepatitis A provide you with a protective antibody?
yes, the IgG is protective
is hep A acute or chronic?
acute (can kill you in couple wks)
how do you prevent hep A
hygiene (hand washing)
sanitation (clean water sources)
immune globulin (pre and post exposure) hep A vaccine (pre exposure)
how is hep A transmitted?
fecal oral
uses of hep A immunoglobulin
pre-exposure:
travelers to HAV-endemic areas
post-exposure (within 2 wks)
how to diagnose hep E?
hep E Ab (hep E IgM represents acute, hep E IgG represents previous exposure and now immune)
does hep IgG protect against future infection?
yes
tx for acute hep E
supportive
presence of HBeAg represents
lot of virus in bloodstream
presence of anti-HBe represents
seroconversion-means you have cleared virus from the bloodstream
seroconversion for hep B occurs in whom?
adults