010915 anatomy liver Flashcards
common hepatic duct
after merging of R and L hepatic ducts
what drains into the sphincter of oddi?
common bile duct and main pancreatic duct
what’s in the portal triad?
portal vein
proper hepatic artery
common bile duct
pancreas is peritoneal or retroperitoneal?
retroperitoneal
portal lobule of liver
looks at exocrine function of liver
has portal triad in the center
hepatic acinus
splits acinus into three zones
diamond shaped
classic lobule of liver
hexagonal shaped with central vein in the middle
Kuppfer cells are located in
sinusoids of liver
how does the gallbladder concentrate bile?
absorbs water, Na and Cl so that bile salts, cholesterol, lecithin, and bilirubin are concentrated
what keeps cholesterol in the gallbladder from forming gallstones?
it’s solubilized by BILE SALTS
fxn of bile salts
emulsification-to break fat into smaller particles
forms micelles
effect of CCK on liver
fatty foods in duodenum cause release of CCK
CCK causes:
- -gallbladder contraction and emptying (Ach from vagus is weaker stimulus)
- -relaxation of the sphincter of Oddi
effect of secretin on liver
acts on biliary epithelium (bile ducts from the liver) to produce a solution rich in sodium bicarbonate
the purpose of this is to help neutralize acids and optimize pancreatic fxn
in the ileum, what happens to bile acids?
they can be reabosrbed through portal blood to go back to the liver
pancreatic acini and ducts fxn to do what?
acini: secrete digestive enzymes
ducts: secrete bicarb rich solution (like the liver)
what digestive enzymes does pancreas secrete for breaking proteins?
trypsin, chymotrpsin, carboxypolypeptidase (all secreted in inactive form)
how are carbs broken down?
ptyalin (saliva)- 20-40%
pancreatic amylase- 50-80%
these two enzymes break down starches to maltose and 3-9glucose polymers
pancreatic lipase works on what?
emulsified fat (emulsified by bile)
products formed in reaction catalyzed by pancreatic lipase?
fatty acids and monoglycerides
where is bicarbonate made?
in ductule cells, which secrete into the pancreatic and biliary ducts
CCK’s effect on pancreas
causes acini to produce digestive enzymes
secretin’s effect on pancreas
causes pancreatic duct epithelium to produce bicarbonate rich solution