011. Skin manifestations of systemic disease

Question 1

What are the different causes of eyrthema nodosum?

Answer 1

Sarcoidosis

Drugs (sulfonamides, contraceoptive pill, dapsone)

Streptococcal infection

IBD

BCG vaccination

leptospirosis
TB

Question 2

What is erythema multiforme.

What are the different causes?

Answer 2

Target lesions, symmetrical and central blisters

Steven johnsons syndrome

Rarely collagen disorders

Question 3

What is the name of the lymes disease rash?

Describe he lymes disease rash

Answer 3

Erythema migrans

Large eryhtematous ring with central fading

Question 4

What is pyoderma gangrenosum

What conditions are associated iwth it?

Answer 4

Recurring nodulo-pustular ulcers with necrotic edges

IBD
Autoimmune hepatitis
Grnaulomatosis with polyangitis (wegner's)
Myeloma
Neopasia

Question 5

What are Gottren’s papules?

Answer 5

Rough red papules on the knuckles adn extensor surfaces

May come with shaws sign rash on eyelids

Associated with dermatomyositis, lung bowel, ovarian or pancreatic malignancy

Question 6

What rash is associated with coeliac disease?

Answer 6

Dermatitis herpetiformis- itchy blisters in groups on knees elbows and scalps

Question 7

What rash is associated with hy[erthyroidism?

Answer 7

Oretibial myoedema- red odematous swellings above the lateral malleoli