01 Kutkot Kokote Flashcards
a single discrete neuroanatomical locus that can account for all the signs and symptoms
focal lesion
involves more than one locus, but loci remain discrete
multifocal lesion
indicates widespread dysfunction of a part of the nervous system
diffuse localization
negative symptoms
reduction of function (weakness, numbness) complete loss (paralysis, analgesia)
positive symptoms
brief and very intense/paroxysmal (seizures)
episodic and recurrent (hemifacial spasm)
loss of function that may be defined on examination
deficit
spell
transient and self-limited abnormality
sudden/ abrupt/ acute onset
seconds to hours
can be vascular, traumatic, or physiologic
subacute onset
days to weeks
can be infectious, toxic, or metabolic
insidious, gradual onset
months to years
can be degenerative, neoplastic, or nutritional
recurrent-remittent onset
episodic attacks with recovery in between
chronic progressive onset
months to years
implies gradual deterioration
umn weaknesses
due to interruption of corticospinal/bulbar tracts increased tone (spastic) increased reflexes (+) babinski (-) atrophy (-) fasciculation
lmn weaknesses
due to involvement of spinal anterior horn (or CN) itself and all distal parts dec tone dec reflexes (-) babinski (+) atrophy (+) fasciculation
in central lesions ___ is interrupted and ___ is weak
corticobulbar fibers, contralateral lower face
in peripheral lesions ___ is interrupted and ___ is weak
nucleus/CN itself, ipsilateral forehead and lower face
tract for position and vibration sensation
ipsilateral posterior column
tract for pain, non-discriminating touch, and temp
contralateral spinothalamic tract
transient monocular blindness is also known as __ and caused by ___
amaurosis fugax, thromboembolism of the retinal artery
cerebellar truncal ataxia
manifests as broad based gait or titubation
associated with involvement of vermis
middle peduncle of cerebellum is:
Largest peduncle, largest pathway, largest part of the pons, ends in the largest lobe of cerebellum
Lateralest
Latest phylogenetically
Simplest (pontocerebellar fibers)
rules of 4 in the brainstem: 4 structures in midline
motor pathway
medial lemniscus
medial longitudinal fasciculus
motor nucleus and nerve
rules of 4 in brainstem: 4 motor nuclei in midline
CN 3, 4, 6, 12