01 - CBC

Question 1

1. PCV = ?

Answer 1

1. % of whole blood composed of RBC

Question 2

1-3. 3 layers that form after centrifuge?

Answer 2

1. plasma
2. RBCs
3. buffy coat (leukocytes and platelets)

Question 3

1. plasma protein conc determined how?
2. falsely ^ by what?

Answer 3

1. refractometry
2. hyperlipidemia

Question 4

1. hemoglobin conc is an index of the RBC mass per unit volume of blood - provides similar info to that of what?

Answer 4

1. PCV

Question 5

(Mean Cell volume)

1. reflects what?
2. ^ = ?
3. dec = ?
4. normocytic = ?

Answer 5

1. RBC size
2. ^ red cell turnover
3. defective red cell growth
4. normal…

Question 6

RDW = ?

Answer 6

red cell distribution width

describes width of the size distribution curve of the RBCs

Question 7

1. what species have twice the platelets and also have macroplatlets that can be read as RBCs?

Answer 7

1. cats

Question 8

(reticulocytes)

1. indicative of what?
2. how long to appear in circ?
3. what animal don’t release?

Answer 8

1. regeneration
2. RBCs
3. horses

Question 9

anisocytosis =

Answer 9

variation in RBC size

Question 10

(RBC shapes)

poikilocytes = ?

Answer 10

abnormally shaped RBCs

Question 11

(rbc shapes)

(schistocytes)

1. RBC fragments caused by what?
2. when two or more spicules called what?

Answer 11

1. intravascular trauma (DIC)
2. keratocytes

Question 12

(rbc shapes)

(acanthocytes)

1. spiculated RBCs with unevenly distributed surface projections
2. often result from what?
3. common cause in cats?

in dogs?

Answer 12

2. changes in cholesterol or phospholipid concentrations in RBC membrane
3. hepatic lipidosis

hemangiosarcoma

Question 13

(rbc shapes)

(echinocytes)

1. spiculated RBCs with evenly distributed surface projections
2. 5 causes?

Answer 13

2. artifact, renal dz, lymphoma, snake bite, chemo

Question 14

(rbc shapes)

(spherocytes)

1. lack central pallor (easiest to see in dogs)
2. caused by what?

Answer 14

2. IMHA

Question 15

(rbc shapes)

(eccentrocytes)

1. how do they look?
2. caused by what?

Answer 15

1. hemoglobin on one side
2. oxidative dmg (occur w/ Heinz bodies)

Question 16

(rbc shapes)

(leptocytes)

1. what are they?
2. cause?

Answer 16

1. RBCs with excess membrane
2. EDTA tube artifact

Question 17

(rbc shapes)

(codocytes)

1. little significance - seen in animals with what?

Answer 17

1. ^ cholesterol

Question 18

(rbc shapes)

(stomatocytes)

1. RBCs with a mouth - look at the name - genetic in dogs

Question 19

(rbc colors)

1. polychromasia indicates what?

Answer 19

1. presence of young erythrocytes

Question 20

(rbc colors)

1. hypochromic RBCs are pale and have dec hemoglobin -> usually from what?

Answer 20

1. iron deficiency

Question 21

(structures in or on RBCs)

(heinz bodies)

1. caused by what?

Answer 21

1. oxidant damage

(appear blue with methylene blue stain)

Question 22

(RBC structures)

(basophilic stippling)

1. aggregates of ribosomes into small granules
2. caused by what?

Answer 22

2. lead poisoning (also see in immature ruminants)

Question 23

(RBC structures)

(nucleated RBCs)

1. indicative of what?

Answer 23

1. regenerative anemia, nonfunctioning spleen, steroids

Question 24

(RBC structures)

(Howell-Jolly bodies)

1. nuclear remnants in RBCs that appear as dark staining, round inclusions
2. associated with what?

Answer 24

2. regen anemia, suppressed splenic fxn

Question 25

(RBC structures)

(siderotic granules)

1. visible iron granules
2. assoc w. what?

Answer 25

2. chloramphenicol, myelodysplasia, impaired heme synth

Question 26

(RBC structures)

1. see virus inclusions in what dog disease?

Answer 26

1. canine distemper

Question 27

1. rouleaux normal in what animal?
2. increases with what?

Answer 27

1. horses
2. plasma protein conc

Question 28

agglutination is associated with what?

Answer 28

IMHA