Zoonotic Disease Flashcards
zoonosis
any disease or infection that is naturally transmissible from vertebrate animals to humans
what percent of existing disease in humans are zoonoses?
60%
what percent of new diseases in humans are zoonoses?
75%
why are there so many emerging zoonoses?
more direct contact with animals in pet and food animal environments
climate change has lead to habitat displacement and more encroachment on wildlife
what are the five stages of zoonotic disease?
- pathogen is present in animals but does not infect humans under normal conditions (feline distemper)
- pathogen can be transmitted from animals to humans but cannot be spread from human to human (Nipah)
- pathogen can be transmitted from animals to humans and can pass between humans. pathogen is not well adapted and will die put after a few cycles of transmission (Ebola)
- pathogen can be transmitted from animals to humans and can pass between humans. can adapt to living in humans for long period of time without going back to animals (cholera)
- pathogen that exclusively infects humans. pathogen may have co-evolved with humans recently and evolved into a specialized human pathogen (HIV)
what people are more susceptible to zoonoses?
infants
children
pregnant women
people undergoing chemo
immunocompromised
elderly
occupation with animals
what animals are more susceptible to zoonoses?
immunosuppressed
higher producing
reptiles
young animals
animals with diarrhea
exotic and wild animals
common zoonotic disease in dogs
rabies
ringworm
salmonellosis
leptospirosis
lyme
campylobacter
giardia
roundworms
hookworms
tapeworms
scabies
rabies stats
1 fatality causing zoonosis
more than 59000 deaths a year
death most common in children
rabies characteristics
bullet shaped neurotropic virus
transmitted by bats in NA, dogs in other countries
rabies symptoms
aggressiveness, hallucinations, fever, nausea, foaming at the mouth, fear of water
leptospirosis
has been found in almost all species of mammals
found in soil and water
prevalent in developed and developing countries
human infections are most commonly caused by contaminated water sources
leptospirosis symptoms
liver or kidney disease
fever, lack of energy, lack of appetite, red eyes, vomiting, jaundice, frequent urination, abdominal pain
leptospirosis clinical presentation
biphasic
septicemic phase lasts about a week and is followed by immune phase which is characterized by antibody production and excretion of leptospirosis in the urine
campylobateriosis
affects cattle, sheep, goats
transmitted to humans by raw milk, undercooked meat, cross contaminated food, etc and direct contact with animals or feces