Zoonoses Flashcards
What is the WHO definition of a zoonoses?
Infections that are naturally transmitted between vertebrate animals and humans
Where is source of disease in zoonoses?
Animals
What are NOT zoonoses and why?
Malaria
Schistosomiasis
Oncoceriasis
Elephantiasis
Transmitted by animals, but depend on the human host for part of their life-cycle
What are anthroponosis?
An infectious disease in which a disease causing agent carried by humans is transferred to other animals
What are examples of anthroponosis?
Influenza
Strep throat
Leishmaniasis
Chytridiomycosis
What can zoonoses by caused by?
Virus, bacteria, parasites or fungi
What are examples of bacterial zoonoses?
Salmonella Campylobacter Shigella Anthrax Brucella E.coli Leptospirosis Plague
What are examples of zoonotic viruses?
Rabies Avian flu Crimean-Congo haemorrhage fever (CCHF Ebola Laa fever West Nile fever Yellow fever
What are examples of parasitic zoonoses?
Cysticercosis Echinococcosis Toxoplasmosis Trichinellosis Visceral larva migrans
What are examples of fungal zoonoses?
Dermatophytoses
Sporotichosis
What are the most common zoonoses in the UK?
Salmonella
Campylobacter
Toxoplasma
Ringworm/dermatophytosis
What are rare zoonoses for the UK?
Anthrax
Rabies
Bubonic plague
What are emerging zoonoses?
A zoonosis that is newly recognised or newly evolved, or that has occurred previously but shows an increase in incidence or expansion in geographical, host or vector range
What is rabies?
A viral infection transmitted from bite of infected animal
What are the main transmitters of rabies?
Dogs, bats, monkeys
What is the incubation period in humans for rabies?
2 weeks to several months
What does rabies do once in the body?
Travels to the brain via peripheral nerves and causes acute encephalitis
What are the signs/symptoms of rabies?
Malaise, headache, fever Progressing to mania, lethargy & coma Over production of salvia & tears Unable to swallow & hydrophobia Death by respiratory failure
How is diagnosis of rabies made?
PCR of saliva or CSF
What is the prognosis of rabies if untreated?
Fatal
What is the management for rabies?
Post-exposure prophylaxis
Human rabies immunoglobulin (HRI)
+4 doses rabies vaccine over 14 days
What is brucellosis?
Highly contagious zoonosis caused by ingestion of unpasteurized milk or undercooked meat from infected animals, or close contact with their secretions
What did brucellosis used to be an occupational hazard of?
Farmers, vets, slaughterhouses
How are the organisms excreted in brucellosis?
In milk, placenta and aborted foetus
How are humans infected by brucellosis?
During milking
During parturition
Handing carcasses
Consumption unpasteurised dairy products
What are the 3 species of brucella?
Melitensis
Suis
Abortus
What is the incubation period for brucellosis?
5-30 days (up to 6mo)