YR 4 EXAM Flashcards

1
Q

Which drugs can cause parkinsonism?

A

those with antidopaminergic effects

eg. typical antipsychotics, metoclopramide

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2
Q

what organism causes scarlet fever?

A

group A strep eg strep pyogenes

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3
Q

treat staggered paracetamol overdose

A

immediate n acetyl cysteine

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4
Q

how does ventricular septal defect present?

A

systolic murmur

signs of heart failure eg hepatomegaly

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5
Q

What age does Perthes present?

A

4-9

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6
Q

What exam finding suggests SUFE?

A

loss of IR

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7
Q

what do exclamation mark hairs indicate?

A

alopecia areata

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8
Q

What presents with a white lace on the buccal mucosa?

A

lichen planus

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9
Q

What is the main metabolic disturbance in DKA?

A

inc lipolysis

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10
Q

What antibodies are present in PBC?

A

AMA

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11
Q

what is spondylosisis?

A

OA of facet joint

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12
Q

what is spondylolithesis?

A

forward slippage of vertebrae

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13
Q

which ankle injury is most common?

A

inversion –> anterior talofibular sprain

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14
Q

what congenital problems are most linked with T1DM?

A

neural tube defect and cardiac disease

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15
Q

which CURB65 score should be managed

a) as an outpatient?
b) in a hospital ward?
c) in a high dependency setting?

A

a) 0-1
b) 2
c) 3

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16
Q

how is MODY inherited?

A

autosomal dominant

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17
Q

How does gilbert’s present?

A

jaundice during periods of stress

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18
Q

How does biliary atresia present?

A

prolonged neonatal jaundice

conjugated bilirubinaemia: pale stools, dark urine

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19
Q

How does bronchiectasis present?

A

daily cough + sputum

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20
Q

What is another name for pulmonary fbrosis?

A

fibrosing alveolitis

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21
Q

How is spontaneous bacterial peritonitis investigated?

A

diagnostic aspiration

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22
Q

What can cause hypokalaemia?

A

loop and thiazides

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23
Q

What DMARD is first line in rhuematoid?

A

methotrexate

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24
Q

Should opiate doses be changed in AKI?

A

reduce as can decrease excretion causing toxicity

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25
Q

How is neuroleptic malignant syndrome

a) diagnosed?
b) treated?

A

a) raised ck

b) bromocriptine

26
Q

which lobe is implicated first in alzheimer’s?

A

temporal

27
Q

which organism causes pneumonia following flu?

A

s aureus

28
Q

what is a conversion disorder?

A

loss of motor/sensory function

29
Q

what is a somatisation disorder?

A

multiple symptoms

30
Q

how does wernickes present?

A

opthalmoplegia
nystagmus
ataxia
confusion

31
Q

how does korsakoff present?

A

amnesia + confabulation

32
Q

how is anterior uveitis managed?

A

topical steroids and mydriatics

33
Q

Which condition is associated with

a) scleritis?
b) ant uveitis?

A

a) rheumatoid

b) IBD

34
Q

manage ? TIA

A

immediately give 300mg aspirin and refer to specialist in next 24hrs

35
Q

Which antibiotic should not be prescribed with

a) methotrexate?
b) warfarin?

A

a) trimethoprim

b) erythromycin

36
Q

Which type of dementia presents with visual hallucinations?

A

lewy body dementia

37
Q

manage myxoedema coma

A

levothyroxine and hydrocortisone

38
Q

how should an ectopic with a foetal heartbeat be managed?

A

surgically

39
Q

what can rapid correction of hyponatraemia cause?

A

central pontine demyelination

40
Q

what can rapid correction of hypernatraemia cause?

A

cerebral oedema

41
Q

ACEi and which drug can cause hyperkalaemia?

A

spironolactone

42
Q

When is postpartum contraception requried from?

A

21 days

43
Q

how should supraventricular tachycardia be managed?

A

vagal manoeuvre then 6mg adenosine

44
Q

what causes bilious vomit in first days of life?

A

malrotation w volvulus

45
Q

How is a suspected PE managed?

A

DOAC eg rivaroxaban

46
Q

what is the difference between critical and acute limb ischaemia?

A

critical - constant pain for >2wks

acute - 6ps pale pulseless

47
Q

how does left ventricular free wall rupture present?

A

inc jvp
muffled heart sounds
acute heart failure

48
Q

which electrolyte disturbance can pancreatitis cause?

A

hypocalcaemia

49
Q

manage threadworm

A

oral mebendazole

50
Q

which medication treats

a) acute menieres?
b) prevents menieres?

A

a) prochloperazine

b) betahistine

51
Q

What vol of maintenance fluids should be given?

A

25 ml/kg/day

52
Q

investigate resp function in myasethenic crisis

A

fvc

53
Q

investigate unprovoked dvt

A

CT chest abdo pelvis for malignancy

54
Q

which virus is associated with

a) nasopharyngeal cancer?
b) oropharyngeal cancer?

A

a) EBV

b) HPV

55
Q

Haematuria + masses in both flanks is indicative of what

and how is it investigated?

A

AD PKD

US renal tract

56
Q

A 50 year old woman has 6 months of increasing fatigue and pruritus. There is no history of foreign travel, injections or blood transfusions. She drinks minimal amounts of alcohol.She is jaundiced.Investigations:Albumin 32 g/L (35-50)Alanine aminotransferase 60 IU/L (10-50)Alkaline phosphatase 920 IU/L (25-115)Bilirubin 55 μmol/L (<17

A

PBC

57
Q

A 33 year old woman and her 32 year old husband have a two year history of primary subfertility. She has an irregular menstrual cycle and her cycles have previously been shown to be anovulatory. Tubal patency has been confirmed. She has an elevated serum free androgen index and a reduced serum sex hormone binding globulin. Her body mass index is 44 kg/m2. Her husband is fit and well.What is the most appropriate investigation?

A

TVUS for ?PCOS

58
Q

Give example of a gram +ve diplococcus

A

strep pneumoniae

59
Q

A 36 year old man is admitted to a psychiatric unit. His speech is very rapid and he does not pause for breath between sentences. He says to the admitting doctor “You’re a doctor, Doctor Who, he’s a doctor, I watch him on TV, I like TV”.

A

flight of ideas

60
Q

A 50 year old man has a 3 week history of fresh haematemesis. For 3 months he has been experiencing epigastric pain and early satiety.

A

gastric cancer

61
Q

A 40 year old man has a painless enlarged left testicle. He was hit in the groin by a football during a game 2 days earlier.There are no groin hernias and the right hemiscrotum is normal. The left testicle has a diffuse swelling in the upper pole that does not transilluminate.

A

seminoma