Year 12 Homework Retrieval Practice 1 Flashcards
Describe how injection of antigen in a vaccination produces immunity
- Vaccines contain antigens as dead or weak pathogens
- A specific immune response takes place
- Memory cells are made
- On second exposure, memory cells produce plasma cells quickly and in large numbers
- Plasma cells rapidly produce antibodies
- Antibodies destroy pathogens
- Herd immunity occurs - fewer people to pass on disease
Draw a diagram to compare antibody production in the primary and secondary response
Give and explain the 3 differences between active and passive immunity
Active involves the production of antibodies by plasma cells and results in production of memory cells, whereas in passive, antibodies are introduced into the body from outside sources, e.g. given by mother or antiserum
Active is long term because antibodies and memory cells are produced in response to the antigen, so the secondary response will occur if the pathogen is met again. However, passive is short term because the antibodies given will be broken down by the body
Active is slow acting as it involves clonal selection and clonal Expansion which takes time, but passive is fast acting because it doesn’t.
Compare and contrast the structure of the walls of arteries and veins in relation to their function (2 similarities and 5 differences)
Similarities:
1) they both have inner endothelium which is smooth and reduces friction
2) they both contain some elastic tissue
Differences:
1) the artery has lots of elastic tissue to stretch under high pressure and recoil, maintaining a constant pressure. However, the vein doesn’t have as much elastic tissue as the pressure is lower
2) the artery has a thicker wall than veins because it has a higher blood pressure
3) veins have large lumen which reduce the resistance, causing a lower blood pressure, compared to the artery which has a smaller lumen to maintain a higher blood pressure
4) arteries have lots of smooth muscle for vasoconstriction, veins do not have lots of smooth muscle
5) veins have valves to prevent backflow of the low pressure blood, but most arteries do not have valves ( exception is the pulmonary artery and aorta)
Name the blood vessels which supplies blood to the heart muscle
Coronary arteries
Explain the cardiac cycle
1) Atrial systole:
- the atria contract simultaneously to force blood into the ventricles.
- this increases the pressure in the atria above that of the ventricles, causing the atrioventricular valves to open
- the blood flows out of the atria into the ventricles
2) Ventricular Systole:
- The atria relaxes, the ventricles contract from the base up and force the AV valves shut (lub), to stop the blood from flowing back,
- the ventricles continue to contract and open the semilunar valves, and blood leaves the heart via the aorta and pulmonary artery.
- the pressure in the ventricles increases above that of the atria, forcing the AV valves shut so backflow can’t happen,
Diastole:
- The ventricles relax, and the semilunar valves shut (dub).
- The AV valves open and the whole heart fills with blood.
Describe how tissue fluid forms
1) There is a high hydrostatic pressure at the arterial end of the capillary, due to the contraction of the left ventricle. The hydrostatic pressure is higher than the osmotic pressure pushing the tissue fluid back into the capillaries.
2) this forces water and other dissolved substances out of the capillary.
3) the hydrostatic pressure falls from the arteriole end of the capillary to the venule end of the capillary, due to this loss of water and also due to friction against the endothelium lining
4) when the water leaves the capillary, plasma proteins are too large to leave the capillary. This increasing concentration of blood proteins reduces the water potential of the blood, which causes the water potential of the blood plasma to increase from the arterial end to the venous end of the capillaries. This high water potential causes water to move back into the capillary by osmosis.
Any tissue fluid not re-absorbed by the venule end of the capillary must be absorbed into the lymphatic system and returned to the circulation at the subclavian vein.
How does high blood pressure effect tissue fluid
High blood pressure (hypertension) leads to an accumulation of tissue fluid (oedema).
How this happens:
- high blood pressure means there’s a high hydrostatic pressure, which increases the outward pressure from the arteriole end of the capillary (and reduces the inward pressure at the venule end of the capillary). Therefore, more tissue fluid is formed and less can be reabsorbed. The lymphatic system is not able to drain the excess fast enough
Explain why starving causes tissue swelling
This causes a reduction in plasma proteins, meaning it can’t reduce the water potential as much as water. This reduces the water potential gradient between the blood and the tissue, so less tissue fluid is reabsorbed at the Venus end of the capillary
More fluid in tissues causes swelling
How does an enzyme lower activation energy
By selling reactants and stressing bonds
Draw an ATP molecule
Describe how insects exchange gases with the environment
Via tracheal system - because they use up oxygen for respiration and release carbon dioxide, this creates a concentration gradient with a high concentration of carbon dioxide and low concentration of oxygen in the bug,
Oxygen diffuses from the air outside through small holes called spiracles and down the trachea. The tracheoles transport the oxygen gas to all tissues.
Respiration occurs in the cells of respiring tissue and carbon dioxide is produced. The carbon dioxide diffuses from tissues down the tracheoles, down the trachea and out of the spiracles into the air
What is the role of the enzyme ATP hydrolase
Hydrolyses ATP to adenosine diphosphate (ADP) and an inorganic phosphate group (Pi).
What is the hydrolytic enzyme within lysosomes called
Lysozymes
Define the term antigen
A foreign protein which causes a specific immune response which results in the production of specific antibodies
What is the term to describe the formation of an antigen - antibody complex
Agglutination
Draw and label a nucleotide
What do monoglycerides, fatty acids and bile salts make
Micelles
Give the formula for rate of diffusion
a means proportional