Yan Flashcards by Daniel Allen

Q

Vitamin K antagonist?

A

warfarin

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Q

bivalirudin drug class?

A

direct thrombin inhibitor

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Q

dabigatran drug class?

A

direct thrombin inhibitor

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Q

argatroban drug class?

A

direct thrombin inhibitor

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Q

rivaroxaban drug class?

A

active factor X inhibitor

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Q

edoxaban drug class?

A

active factor X inhibitor

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Q

Apixaban drug class?

A

active factor X inhibitor

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Q

fondaparinux drug class?

A

active factor X inhibitor

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Q

Intrinsic pathway is associated with?

A

surface contact

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Q

Extrinsic pathway is associated with

A

tissue factor

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Q

Factor XIIa

pathway?
inhibited/inactivated by?

A

pathway: intrinsic

inactivated by: heparin

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Q

Factor XIa

pathway?
inhibited/inactivated by?

A

pathway: intrinsic

inactivated by: heparin

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Q

Factor XII

intrinsic or extrinsic?

A

intrinsic

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Q

Factor XI

pathway?

A

intrinsic

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Q

Factor IX

pathway?

A

intrinsic

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Q

Factor IXa

pathway?
inhibited/inactivated by?

A

pathway: intrinsic

inactivated by: heparin

Q

Factor X

inhibited/inactivated by?

A

inhibited by warfarin

Q

Factor VIIa

pathway?
inhibited/inactivated by?

A

pathway: extrinsic

inactivated by: heparin

Q

Factor VII

pathway?
inhibited/inactivated by?

A

pathway: extrinsic

synthesis inhibited by: warfarin

Q

Factor Xa

inactivated/inhibited by?

A

inactivated by: heparin

Q

Thrombin

inactivated/inhibited by?

A

inactivated by: heparin

Q

rivaroxaban works via inhibition of what factor?

A

Xa

Q

dabigatran works via inhibition of what?

A

thrombin

Q

bivalirudin works via inhibition of what?

A

thrombin