Y12 MS - Transport Across Membranes (Complete) Flashcards
What is shown by A?
Phospholipid
A1 - Hydrophilic phosphate head
A2 - Hydrophobic fatty acid tails
What is shown by B?
Glycolipid
What is shown by C?
Glycoprotein
What is shown by D?
Carbohydrate
What is shown by E?
Cholesterol
What is shown by G?
Channel protein (intrinsic)
What is shown by F?
Extrinsic protein
How are the phospholipids arranged in the cell membrane?
In a bilayer
- Hydrophilic phosphate heads face outwards
- Hydrophobic fatty acid tails face inwards
Are the phosphate heads and fatty acid tails or phospholipids polar or non-polar?
Phosphate heads - polar
Fatty acid tails - non-polar
Why are the fatty acid tails in the cell membrane important?
The fatty acid tails are hydrophobic so prevent water soluble molecules from crossing the membrane
Therefore, a barrier is created between the cytoplasm and the fluid outside of the cell
True or false? The membrane is fluid
The membrane IS fluid
The phospholipids move laterally meaning that the cell membrane can is fluid
What is the function of channel proteins?
Channel proteins span the membrane (intrinsic) and form water filled channels
This means that small, water soluble molecules are able to diffuse across the channel proteins and into or out of the cell
What is the function of carrier proteins
Carrier proteins have a binding site for a specific chemical and transport them across the membrane
The cell membrane is ———— —————. What does this mean?
The cell membrane is selectively permeable so only allows some chemicals to cross the membrane
The cell membrane is modelled by the fluid mosaic model. What does this mean?
Fluid - the phospholipids are able to move around laterally
Mosaic - the proteins within the phospholipid bilayer form a scattered, mosaic pattern when viewed from above
Phospholipids can form a bilayer. What is the other arrangement of phospholipids which can be formed?
A micelle
This is formed when phospholipids are shaken / mixed with water
What is the function of glycolipids and glycoproteins?
They are used as cell recognition sites
The pattern of the carbohydrate units act as antigens on the surface of the cell
What is the function of cholesterol in the cell surface membrane
Cholesterol decreases the fluidity of the membrane by linking phospholipids together, making the structure more stable so it doesn’t split apart
What is diffusion
The net movement of a substance down a concentration gradient
What is Ficks Law?
The rate of diffusion is proportional to
(Surface area x concentration gradient) / diffusion distance
What are the common adaptations for to increase the rate of diffusion
Large surface area
Short diffusion distance
Maintained diffusion gradient
What is simple diffusion in the cell membrane
Where small, non-polar molecules pass across the cell membrane by diffusion (intrinsic proteins not required)
What type of molecules can move across the cell membrane by simple diffusion
Small and non-polar e.g oxygen, fatty acids, carbon dioxide, fat-soluble vitamins
Where does facilitated diffusion occur in the cell membrane
Intrinsic proteins in the cell membrane facilitate (help) the movement of polar molecules across the membrane
- Uses channel / carrier proteins