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GI Pharm > Xerostomia Drugs > Flashcards

Xerostomia Drugs Flashcards

1
Q

muscarinic agonists for tx of xerostomia

A

cevimeline and pilocarpine

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2
Q

MOA of cevimeline

A

muscarinic agonist (M3 > M1)

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3
Q

cevimeline CI

A

asthma, closed angle glaucoma, iritis

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4
Q

cevimeline precautions

A

angina, breast-feeding, bronchitis, cardiac, COPD, driving, nephrolithiasis, pregnancy

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5
Q

cevimeline DDI

A

b-blockers

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6
Q

cevimeline CYP interactions

A

CYP3A/4, CYP2D6

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7
Q

pilocarpine MOA

A

muscarinic agonist, ALL M receptors & crosses BBB

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8
Q

pilocarpine CI

A

asthma, closed angle glaucoma, iritis

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9
Q

pilocarpine precautions

A

same as cevimeline (angina, breast-feeding, bronchitis, cardiac, COPD, driving, nephrolithiasis, pregnancy)
PLUS
psychosis (crosses BBB)

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GI Pharm (6 decks)

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