Xenobiotics- Heavy metal tolerance Flashcards

1
Q

How are heavy metals release and effects

A

processing of metals
fossil fuel burning

contaminate, persist and bioaccumalate

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2
Q

What are the methods of heavy metal tolerance

A

Hyperaccumalation
Inactivation of heavy metals
Active eflux transporters

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3
Q

How can heavy metals be inactivated

A

Metallothiones- cysteine rich proteins that form s-s bonds in a non specific manner

Phytochelatins- oligomers of glutione
Heavy metal binding to gluthione makes it to form faster by enzymes

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4
Q

How can heavy metals be inactivated

A

Metallothiones- cysteine rich proteins that form s-s bonds in a non specific manner

Phytochelatins- oligomers of glutione
Heavy metal binding to gluthione makes it to form faster

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5
Q

Examples of how heavy metals be effluxed and influxed

A

copper efflux pump- pathway formed by 5 methoine pairs

Zinc transporter-Hzip
Histidine residues indicated for transport of zinc

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