X-linked dominant Flashcards
1
Q
How do x-linked dominant disorders work with dads?
A
If dad has an affected X chromosome, the ALL daughters will have it and NO sons will have it.
2
Q
How do x-linked dominant disorders work with moms?
A
If mom has an affected X chromosome, then 50% of her children will have it.
There are NO carriers with a dominant trait. This is the same pattern for Autosomal dominant.
3
Q
What are 4 x-linked dominant disorders?
A
- X-linked hypophosphatemic rickets
- Pseudohyperparathyroidism
- Aicardi syndrome
- Alport syndrome
