Wounds Flashcards

1
Q

Clean wound

A
  • Surgical prep
  • GI tract not entered
  • Primary closure
  • No abx
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2
Q

Clean- contaminated wound

A
  • Surgical prep, enter GI tract
  • Primary closure
  • Cefazolin abx
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3
Q

Contaminated wound

A
  • Trauma with foreign material or spillage of GI contents
  • Debridement, irrigation
  • Secondary closure
  • Oflaxaxin abx
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4
Q

Dirty and infected wound

A
  • Pus at site
  • Necrosis
  • Debridement, irrigation, secondary closure
  • Augmentin
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5
Q

First intention healing

A
  • Suturing or other closure of wound
  • Wound to MD in 12 hrs
  • Best aesthetic and fxn outcome
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6
Q

Second intention healing

A
  • Healing through granulation
  • Increased scarring
  • Wounds contaminated with debris and bites
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7
Q

Tertiary intention healing

A
  • Closure after 3-4 days
  • Allows close monitoring
  • Increased blood flow to wound to encourage healing
  • Immunocomp pts
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8
Q

Substate phase of healing

A
  • Coagulation: fibrin, thromoin and compliment attract inflammation cells
  • Platelets attract leukocytes
  • Interleukins, histamin, serotonin and bradykinin cause constriction then dilation
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9
Q

Proliferative phase

A
  • Fibroplasia and matrix deposition
  • Collagen and proteoglycans form CT matrix
  • Angio genesis in 4 days
  • Epitheliazation- keep moist
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10
Q

Remodeling phase

A
  • Collagen fiber maturation
  • Lysis and contraction
  • Fibroblasts and leukocytes
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11
Q

Infectious agent

A

Bacteria creating toxic metabolites leading to tissues destruction

  • Skin aerobes- strep and staph
  • Clostridium in dead tissue
  • Opportunistic pathogens in immunocompromised
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12
Q

Susceptible host

A
  • Age- reduced cell fxn
  • Immunosuppression- increased susceptibility
  • Steroid- suppress inflammation
  • Stress, pain
  • Smoking- Vasoconstriction
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13
Q

Closed, unperfused space

A
  • Perfusion and oxygenation very important
  • Lack affects natural ability to fight infection
  • Hypercapnia and acidosis increase risk
  • Narrow outlets- gall bladder, appendix
  • Potential spaces
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