Wound Healing and Repair

Question 1

heritable CT disorder where collagen is deficient
A. Ehlers-Danlos syndrome
B. Marfan's syndrome
C. Osteogenesis imperfecta
D. Epidermolysis bullosa

Answer 1

B - Marfan’s syndrome

Question 2

strongest chemotactic factor for fibroblasts:
A. epithelial growth factor
B. insulin like growth factor
C. platelet-derived growth factor
D. transforming growth factor beta

Answer 2

C - platelet-drived growth factor

Question 3

amino acids abundant in collagen molecule:
A. hydroxyproline, hydroxyalanine
B. hydroxyproline, hydroxylysine
C. hydroxyleucine, hydroxyproline
D. hydrosamine, glycosaminoglycan

Answer 3

B - hydroxyproline & hydroxylysine

Question 4

enumerate the stages of wound healing!

Answer 4

1. coagulation
2. inflammation
3. collagen synthesis
4. angiogenesis
5. epithelialization
6. contraction

Question 5

principal type of collagen in scar
A. Collagen type I
B. Collagent type III
C. Collagen type V
D. Collagen type VIII

Answer 5

A - collagen type I

Question 6

enumerate the phases of wound healing!

Answer 6

1. inflammatory phase
2. proliferation phase
3. remodelling phase

Question 7

enumerate the categories of surgical wounds

Answer 7

1. clean
2. clean-contaminated
3. contaminated
4. dirty/infected