Hemostasis, Surgical Bleeding, Transfusion Flashcards
1
Q
Traditionally recognized causes of traumatic coagulopathy include the following except A. Acidosis B. Hypothermia C. Dilution of Coagulation Factors D. Shock
A
D. Shock
2
Q
Patients in shock states induce coagulolopathy through systemic activation of anticoagulant and fibrinolytic pathways. Which is least likely to be true?
A. Hypoperfusion causes activation of thrombomodulin on the surface of the endothelial cells
B. The circulating thrombin complexes with the thrombomodulin
C. The thrombomodulin-thrombin (T-T) complex activates protein C and enhances fibrinolysis
D. The T-T complex suppresses Protein inhibits tissue Plasminogen Activator
A
D. The T-T complex suppresses Protein inhibits tissue Plasminogen Activator
3
Q
Which of the following causes vasodilation? A. Prostacyclin B. Serotonin C. Epinephrine D. Thromboxane2
A
A. Prostacyclin
4
Q
What is the end product of coagulation cascade? A. Tenase complex B. Amorphous Plug C. Fibrin D. Thrombin
A
C. Fibrin
5
Q
In hemostasis, what is considered as the initial response to injury? A. Release of tissue factor B. Activation of factor XII C. Vasoconstriction D. Platelet aggregation
A
C. Vasoconstriction
6
Q
What is the normal life span of platelets? A. 7-10days B. 5 days C. 2 weeks D. 30 days
A
A. 7-10 days
7
Q
What is the main reason why injured veins may remain open and continue to bleed? A. thin muscular layer B. thin adventitia C. thin intima D. thin serosa
A
A. thin muscular layer
8
Q
What is considered initial reaction to injury? A. Activation B. Aggregation C. Agglutination D. Adhesion
A
D. Adhesion
9
Q
Which of the following elements prevents platelets to clump together? A. prostglandin B. serotonin C. epinephrine D. thromboxane2
A
A. prostaglandin
10
Q
What zymogen is activated that starts the cascade in the common pathway of coagulation? A. Fibrinogen B. Anti-hemophilic factor C. Pro-accelerin D. Prothrombin
A
D. prothrombin
11
Q
What group of factors needs a carboxyl group to their glutamic acid residues for them to be effective coagulation factors? A. Factors 1, 3, 5, 8 B. Factors 2, 10, 7, 9 C. Factors 8 & 9 D. Factors 13 & 8a
A
B. Factors 2, 10, 7, 9
12
Q
What is the oldest mechanical method of hemostasis and is also considered the least traumatic haemostat? A. Kelly forceps B. Atraumatic forceps C. digital pressure D. Ligatures
A
C. digital pressure
13
Q
What is considered as the most common abnormality of hemostasis? A. Thrombocytopathia B. Thrombocytopenia C. Dilutional hypofibrogenemia D. Bone marrow depression
A
B. thrombocytopenia
