Wound Healing

Question 1

How long does the haemostatic stage of wound healing last?

Answer 1

a few seconds

Question 2

What occurs in the haemostatic stage of wound healing?

Answer 2

 Prostaglandins released, leads to vasoconstriction. Collagen exposed in damaged vessel wall binds to platelets and initiates clotting cascade. Fibrin mesh forms.

Question 3

How long does the inflammatory phase last?

Answer 3

3-5 days

Question 4

What occurs in the inflammatory phase?

Answer 4

 Vasodilation and increased capillary leakage promotes delivery of nutrients and immune cells to injury site = oedema.

Question 5

Name the 4 stages of wound healing?

Answer 5

Haemostatic
Inflammatory
Proliferative
Remodelling

Question 6

What occurs in the proliferative phase?

Answer 6

 Re-epithelisation
 Angiogenesis
 Collagen synthesis

Question 7

How long does the proliferative phase last?

Answer 7

4 days - 2 weeks after injury

Question 8

What happens during the remodelling stage?

Answer 8

Collagen remodelling

Vascular maturation and regression