Wound Healing Flashcards
What is primary wound healing?
Healing by primary intention:
-Tissue is anatomically re-approximated
Advantages of primary wound healing?
- Easier care
- Faster return of function
- Better cosmetically
Disadvantages of primary wound healing?
Increased risk of infection
What is secondary wound healing?
By secondary intention:
-Wound left open; granulation tissue forms and wound closes by contraction of tissues
Advantages of secondary wound healing?
Infection is nearly impossible
-Good for highly contaminated wounds
Disadvantages of secondary wound healing?
Complicated care
Possible poor cosmetic outcome
What is tertiary wound healing?
Delayed primary closure:
- Wound left open for 5 days w/ wound care then surgically closed
- Abundant granulation tissue-vascular
- Rarely used
How long is inflammatory phase in primary wound healing?
4 days
-Unknown in secondary or tertiary
How long is the maturation and remodeling phase in wound healing?
9-12 months
When does the proliferative phase in wound healing occur?
After epithelium covers wound
Can a chronic wound be converted to an acute wound?
Yes
Do we use systemic ABX for an infected wound?
No, only if there is sepsis or cellulitis
What can inhibit wound healing?
Edema
Pressure
What vitamin is important for collagen production?
Folic acid
What is magnesium important for in wound healing?
Protein synthesis
What role does vitamin A play in wound healing?
Inflammatory response
Macrophages
Collagen
What role does Zinc play in wound healing?
Cofactor in DNA and RNA synthesis
What effect does uncontrolled DM or hyperglycemia have on wound healing?
Impaired collagen formation
Impaired healing
Inhibits fibroblast and endothelial cell proliferation