Wound Heal/inflammation Flashcards
What is the first vascular response for acute (injury) inflammation ?
Brief vasoconstriction (for homeostasis )
What are the three types of inflammation ?
Acute- sudden onset
Sub acute-
Chronic-always there, slow
insidious
What happens to blood flow during cellular response of inflammation
Blood flow SLOWS as fluid is lost
During cellular response, which blood cell is first to respond
WBC: neutrophils (within 6-12 hours)
Which cells increase in response to allergic disorders, inflammation of skin & parasitic infections?
Eosinophils
Describe acute inflammation Vascular response:
- vasoconstriction
- histamines released
- vessels dilate
- hyperemia (increased blood)
- increased capillary permeability
What is the adaptive mechanism of inflammation:
- destroy/dilute injurious agent
- prevent further spread of injury
- remove necrotic materials
- establish healing environment
Describe cellular response of inflammation:
- blood flow slows
- margination occurs
- diapedesis
- Chemotaxis
Which exudate is clear like plasma?
Serous
Which exudate is red with many RBCs?
Sanguineous
Which exudate is described as pinkish, watery with RBCs?
Serosanguineous
What is the final phase of healing?
Regeneration & Repair
Definition of Labile
Easily altered
What meds to consider in inflammatory process that can alter response?
Acetylcytic acid, NSAIDS, CoRticosteroids, acetaminophen
What are the local manifestations of inflammation?
- Redness
- Heat
- Pain
- Swelling
- Loss of function
What is the inflammatory response?
A sequential reaction to cell injury that neutralizes and dilutes the inflammatory agent, removes necrotic materials and establishes a suitable environment for healing and repair.
What are some variables that may affect the physiological tolerance to heat and cold?
- Body part, which parts are temperature sensitive?
- size of exposed body part
- length of exposure
- intactness of skin
- neurosensory impairment
- impaired mental status
- open wounds
What factors to primary prevention may interfere with wound healing?
- Malnutrition
- obesity
- decreased blood supply
- smoking
- tissue trauma
- chemotherapy
- infection