Word Associations Flashcards
concentric hypertrophy
HFpEF
diastolic HF
HFpEF
systolic HF
HFrEF
eccentric hypertrophy
HFrEF
pressure overload
concentric hypertrophy
volume overload
eccentric hypertrophy
CRHD
mitral stenosis
dystrophic calcification
aortic stenosis
fused commissures
CRHD
leaflet neovascularization
CRHD
Marfans
aortic regurg
retraction of valve leaflets
CRHD, aortic regurg
myxomatous degeneration
mitral regurg
torn chordae
mitral regurg
bacterial endocarditis
regurgitation, emboli, glomerulonephritis
NBTE
emboli from valves
tx goal in uncomplicated htn
140/90
tx goal in complicated htn
130/80
activating RAAS
hypo: volemia, natremia, tension, adrenegic activation
deactivating RAAS
angiotensin receptor binding, feedback inhibition
RAAS rate limiting step
renin
AT1
vasoconstriction
AT2
vasodilation
LOX1
angiotensin II –> LDL –> atherosclerosis
NFKB
angiotensin II –> VCAM, MCP1
persistent cough
ACEI effect, bradykinin
apoB
chylomicrons, VLDL, LDL, atherogenic
apoA
HDL
apoE
HDL, VLDL, IDL, not LDL
apoCII
lipoprotein lipase, cofactor, chylomicrons, VLDL
loss of apoE
circulating LDL in endogenous pathway
eruptive xanthomas
hyperchylomicronemia (FCS)
LPL, apoCII mutation
familial chylomicronemia syndrome
tendon xanthoma
familial hypercholesterolemia
pancreatitis
familial chylomicronemia syndrome, severe familial hypertriglyceridemia
cutaneous xanthoma
familial hypercholesterolemia (also FDB, ADH3)
corneal arcus
familial hypercholesterolemia (also FDB, ADH3)
LDL receptor mutation
familial hypercholesterolemia
apoB100 mutation
familial defective apoB (FDB)
PCSK9 GOF
autosomal dominant hypercholesterolemia 3 (ADH3)
VLDL overproduction
familial combined hyperlipidemia (FCHL)
ApoEII mutation
familial dysbetalipoproteinemia (FD)
palmar xanthoma, tuberose xanthoma
familial dysbetalipoproteinemia (FD)
high VLDL, no mutation
familial hypertriglyceridemia (and severe version)
ABCA1 mutation
tangier disease, cholesterol macrophages, low HDL
free cholesterol buildup
LCAT deficiency
corneal cholesterol
LCAT deficiency
ratelimiting in cholesterol
HMG CoA Reductase, statins