Women's Flashcards

1
Q

Symptoms of ovarian cancer

A
  1. Abdominal bloating
  2. Increased abdominal girth
  3. Indigestion or early satiety
  4. Change in bowel habits, specifically constipation
  5. Urinary frequency, incontinence
  6. Abdominal or pelvic pain
  7. Dyspareunia
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2
Q

Potential causes of Ca-125 elevation

A
  1. Ovarian cancer
  2. False positive
  3. Benign ovarian neoplasm
  4. Uterine fibroids
  5. Hepatitis
  6. SLE / autoimmune disease
  7. Bowel ca
  8. Pancreatic ca
  9. Endometrial ca
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3
Q

Contraindication to oestrogen MHT therapy

A
  • hx hormone dependent cancer
  • active hormone dependent cancer
  • past hx thromboembolic disease is relative contraindication (transdermal oestrogen preferable)
  • cardiovascular / cerebrovascular disease is relative contraindication too
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4
Q

Dx criteria for PCOS

A

Rotterdam dx criteria (two of three required)
1. Oligo/anovulation

  1. Hyperandrogenism
    - biochemical (raised FAI or free testosterone)
    - clinical (hirsutism, acne)
  2. Polycystic ovaries on USS
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5
Q

Risk factors for breast ca

A
  • Family history of breast and ovarian cancer
  • Increasing age
  • Late childbearing (after the age of 30 years)
  • Nulliparity (no children)
  • Early menarche (<12 years of age)
  • Late menopause
  • Use of hormone replacement therapy (particularly combined therapy)
  • Ashkenazi Jewish ethnicity
  • Obesity (post-menopausal women)
  • Lifestyle factors (high alcohol consumption, high-fat diet)
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6
Q

DDx breast lump

A
  • Prominent fibroglandular tissue (normal breast tissue)
  • Cyst
  • Fibroadenoma
  • Abscess
  • Lipoma
  • Fat necrosis
  • Haematoma
  • Breast cancer
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7
Q

Hx questions to elicit if female factor underlying cause of infertility

A
  • symptoms of PCOS (hirsutism, acne, irregular menses)
  • symptoms to suggest endometriosis
  • symptoms of prolactinoma (galactorrhea, headache)
  • symptoms of hypothyroidism
  • symptoms to suggest PID
  • symptoms of uterine polyp
  • previous contraception use / depot provera
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8
Q

Causes of bleeding in first trimester

A
  • miscarriage
  • ectopic pregnancy
  • endometrial implantation
  • gestational trophoblastic disease
  • cervical lesions
  • vaginal lesions
  • uterine infection
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9
Q

Options for mx of miscarriage

A
  1. Expectant
  2. Medical
  3. Surgical
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10
Q

Causes of secondary dysmenorrhea

A
  • endometriosis
  • adenomyosis
  • fibroids
  • pelvic infection
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11
Q

Examination findings in someone with endometriosis

A
  • reduced uterine mobility
  • adnexal masses
  • uterosacral nodularity
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12
Q

Common causes of itchy vulvitis in postmenopausal woman

A
  1. Lichen sclerosus
  2. Psoriasis
  3. Dermatitis

(vaginal candidiasis very unlikely in this age group)

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13
Q

Tx for vaginal lichen sclerosis

A

Super potent corticosteroid

- Diprosone 0.05% in optimised vehicle

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14
Q

Mx troublesome bleeding with Implanon

A
  • COCP, taken continuously or cyclically for 3/12
  • 5/7 NSAID Mefenamic acid 500 mg BD to TDS
  • 5/7 Tranexamic acid 500mg BD
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15
Q

Post partum nipple pain - what physical examination is required

A
  • examination breasts and nipples - nipple trauma, breast lumps, swelling or erythema
  • temp
  • baby oromotor assessment - tongue mobility & palate
  • baby weight since birth
  • observation of a breastfeed with consent
  • neonatal examination
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16
Q

Primary amenorrhea causes

failure of menses to start by 16yrs

A
  1. Hypothalamic amenorrhea (exercise, low BMI)
  2. PCOS
  3. Imperforate hymen
  4. Congenital absence uterus / vagina
  5. Chromosomal anomalies
  6. Pituitary tumours
17
Q

Secondary amenorrhea

absence of menses for > 6 months in a woman who has established menstruation

A
  1. Hypothalamic amenorrhea (exercise, low BMI)
  2. PCOS
  3. Pregnancy
  4. Hyperprolactinaemia
  5. Premature ovarian insufficiency
  6. Medication (OCP, antipsychotics)
  7. Thyroid dysfunction
  8. Adrenal disorders (Cushing)
  9. Asherman syndrome
18
Q

How to prescribe MHT

- previous hysterectomy

A

Continuous oestrogen
- transdermal or oral preparation
(transdermal oestrogen has lower VTE risk)

19
Q

How to prescribe MHT

- perimenopausal

A

LMP < 12 months ago

  • cyclical MHT (reduce risk of breakthrough bleeding)
  • after 12 months of cyclical MHT, can switch to continuous

eg. Femoston

20
Q

How to prescribe MHT

- postmenopausal

A

LMP > 12 months ago
- continuous combined oestrogen / progesterone

eg. Angeliq

21
Q

Causes of heavy menstrual bleeding

A
  • uterine fibroids
  • endometrial / endocervical polyps
  • endometrial hyperplasia
  • adenomyosis
  • presence of an IUD
  • hypothyroidism
  • bleeding disorder eg. von Willebrand disease
  • PCOS
22
Q

Second and third trimester bleeding

A
  • bloody show with associated labour
  • early pregnancy loss (< 20 weeks)
  • placenta previa
  • placental abruption
  • uterine rupture
  • vasa previa (rare)
23
Q

RF for urinary incontinence

A
  • parity
  • vaginal deliveries of children
  • FMHx urinary incontinence
  • smoking hx
  • excessive caffeine intake
  • faecal incontinence
  • vaginal atrophy
  • recurrent UTI
  • recent weight gain
  • hx heavy lifting (occupational or exercise)
24
Q

3 invx for urinary incontinence

A
  1. Urine MCS
  2. Bladder diary
  3. Bladder emptying imaging / renal tract USS
25
Q

5 non-pharm mx options for urinary incontinence

A
  1. Limit fluid intake (8 cups / day)
  2. Minimise bladder irritants such as caffeine, alcohol
  3. Maintain healthy BMI
  4. Avoid heavy lifting
  5. Avoid constipation with high fibre diet
  6. Pelvic floor training
  7. Timed voids