women Flashcards
risk malignancy index (RMI) components
S findings, menopausal status and CA125 levels (ovarian)
ovarian cancer risk factors
family history: mutations of the BRCA1 or the BRCA2 gene
many ovulations*: early menarche, late menopause, nulliparity
feature of overian cancer?
abdominal distension and bloating abdominal and pelvic pain urinary symptoms e.g. Urgency early satiety diarrhoea
ovarian cancer investigation
CA125
NICE recommends a CA125 test is done initially. Endometriosis, menstruation, benign ovarian cysts and other conditions may also raise the CA125 level if the CA125 is raised (35 IU/mL or greater) then an urgent ultrasound scan of the abdomen and pelvis should be ordered a CA125 should not be used for screening for ovarian cancer in asymptomatic women
ultrasound
Mx of ovarian cancer
usually a combination of surgery and platinum-based chemotherapy
hoe often id depo injection gievn?
every 12 weeks
usually a combination of surgery and platinum-based chemotherapy
ovarian torsion
features of ovrain torsion?
Usually sudden onset of deep seated colicky abdominal pain.
Associated with vomiting and distress
fever may be seen in a minority (possibly secondary to adnexal necrosis)
Vaginal examination may reveal adnexial tenderness
On which day would you carry out mid-luteal progesterone level?
7 days before the end of the lady’s regular cycle when progesterone levels should be tested