WM 2- Identifying The Active Chemical In Willow Bark Flashcards

1
Q

What is the structure of phenol?

A

OH group is attached to benzene ring

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2
Q

Give order of increasing acidity of phenols, alcohols, water and carboxylic acids

A

Alcohols

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3
Q

How can phenols and alcohols be distinguished from each other?

A
Add iron(III)chloride, 
- Fe3+ forms complex with -C=C-OH in phenols, form purple complex
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4
Q

How do you esterification phenols?

A

Add acid anhydride, to form ester and carboxylic acid

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5
Q

What are the 2 ways to esterify salicylic acid, and what are the products?

A
  1. Esterification of phenol group using acid anhydride, to give aspirin
  2. Esterification of carboxylic acid group using alcohol, to give Oil of Wintergreen
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6
Q

How is aspirin made more soluble?

A

React with NaOH

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