Wk5 Limb Flashcards

1
Q

limb bud

A

A thickened portion of the lateral plate somatic mesoderm which will form the tissues of the limb (excepting the muscles)

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2
Q

apical ectodermal ridge

A

An anterior-posterior ridge of ectoderm running along the distal edge of the limb bud. Signals outgrowth to the limb bud mesenchyme

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3
Q

zone of polarizing activity

A

A region of the posterior margin of the limb bud mesenchyme which signals to promote posterior specification

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4
Q

premuscle masses

A

In the limb bud, dorsal and ventral masses of cells which will form the muscles, derived from the somites

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5
Q

mesenchymal condensations

A

In the limb bud, regions of higher density of mesenchymal cells which pre-figure the limb cartilages (and bones)

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6
Q

polydactyly

A

More than a normal number of digits

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7
Q

syndactyly

A

Fused digits

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8
Q

brachydactyly

A

Short digits

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9
Q

ectrodactyly

A

Split hand split foot

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10
Q

amelia

A

A lack of limbs

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11
Q

phocomelia

A

An absence of intermediate segments of limb

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