wk5 Flashcards

1
Q

what are osteoblasts

A

Produce collagen (support and strength) and proteoglycans (polysaccharide and protein substances that transport minerals): stimulate osteoclast resorptive activity

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2
Q

what are osteoclasts

A

Maintain bone matrix, Resorb bone; assist with mineral homeostasis

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3
Q

what are the disease processes of musculoskeletal system

A
  • Joint disorders
  • Fractures
  • Osteomyelitis
  • Osteoporosis
  • Paget’s disease
  • Rheumatoid arthritis
  • Osteoarthritis
  • Gout
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4
Q

joint disorders

A
  • Strains and sprains
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5
Q

strain vs sprain

A

o Strain- stretching or a partial tear in a muscle or muscle and tendon unit (a complete tear is a rupture)
o Sprain- involve damage to the supporting ligaments of a joint, or the joint capsule

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6
Q

whats a dislocation

A

the loss of articulation of the joint
o Caused by displacement of the bone ends
o Usually the result of severe trauma that disrupts the ligaments holding the bones in position
o May be traumatic, congenital or pathologic
o Signs and symptoms include pain, deformity, limited movement
o Treatment usually reduction, with assistance of pain relief or anaesthesia, and x-ray
o Joint will require immobilisation for several weeks to allow injured joining tissues to heal
o May be complicated by fractures

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7
Q

a herniated disk

A
  • Discs are pads that serve as “cushions” between vertebral bodies

oHarder outer layer surrounds soft inner centre
- Outer layer split or rupture, inner layer centre squeezed outwards

oCommon in L4 & L5 lower back
- Disc tissue can press on the adjacent spinal nerves

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8
Q

whats a fracture

A
  • Occurs when a greater stress is placed on a bone than it can withstand
  • Causes include
    o Sudden injury
    o Fatigue or stress fractures
    o Pathologic fractures
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9
Q

types of fractures

A

o Greenstick- a bend or partial break, common in children as they have more resilient bones
o Impacted- fractured fragments are wedged together
o Compression- two bones crushed together
o Comminuted- more than two pieces of fractured bone

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10
Q

TX of fractures

A

o First aid- ABCDE then splint the fracture- prevent movement and further injury
o Reduction of the fracture
o Immobilisation- to hold in place while healing occurs
o Preservation and restoration of function of the injured part

-	Nursing Interventions
o	ABCDE
o	Pain relief
o	Postoperative elevation of the limb
o	Neurovascular observations of limb- colour, warmth, movement, sensation in extremities, pulse distal to fracture, capillary refill
o	Check for complications- DVT, compartment syndrome
o	Drains
o	Document
o	Nutrition
o	Physiotherapy
o	Social
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11
Q

four stages of bone healing

A

haemotoma formation: blood at fracture site forms a clot. this is the framework of bone repair

fibrocartilaginous callus formation: fibroblasts and osteoblasts migrate to site and begin reconstruction

Ossification: 3rd to 4th week callus is replaced with mature bone, can begin WBAT

Remodelling: reabsorption of callus from marrow space and around fracture site

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12
Q

complications with fractures

A

hypovolemic shock

  • DVT
  • Compartment syndrome
  • Fracture blisters
  • Fat embolism syndrome
  • Osteomyelitis
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13
Q

what is compartment syndrome

A
  • Increased pressure within a confined space
  • Muscles and nerves of a limb are enclosed by a firm layer of tissue called fascia (muscle compartment)
  • If there is much bleeding and/or oedema, increase in the volume of the muscle compartment
    o Fascia does not stretch
    o Pressure will increase inside the muscle compartment
    o Pressure will cause permanent damage to muscles and nerves if not relieved
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14
Q

Tx of compartment syndrome

A
  • Reduce the pressure
  • If limb has a tight cast or dressing- slit these as pressure may be due to this
  • Elevate limb
  • Prepare for surgery- fasciotomy may be necessary to relieve pressure and save the muscles and nerves
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15
Q

what is osteoarthritis

A
  • Surface crack appear in the cartilage surface
  • Cracks widen down to subchondral bone
    o Synovial fluid forms cysts within the bone
  • Articular cartilage becomes eroded, exposed bone becomes polished, thickened and hardened
  • Abnormal bony outgrowths occur at the joint margins – spurs
  • Joint loses its resilience and its structural integrity
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16
Q

S&S of osteoarthritis

A

o Pain- aching; early in disease, relieved by rest
o Joint swelling
o Joint stiffness after periods of immobility
o Crepitus and grinding may be heard/felt in affected joint
- Joints commonly affected include; hip, knee, lumbar and cervical vertebrae, hands, fingers, and toes
o One joint may be affected initially, then may spread to other joints as they take on extra stress in protecting injured joint
o Joint becomes limited in movement and unstable

17
Q

what is rheumatoid arthritis

A
  • Systemic autoimmune disease
  • Joint cartilage is destroyed
  • Synovial tissues become inflamed
  • Abnormal healing process occurs- vascular tissue grows into synovial membrane and bone pannus
  • Pannus growth leads to reduced joint motion and eventually ankylosis (joint fixation, often deformed), subluxation (dislocation of the joint) and joint instability
18
Q

nursing management of rheumatoid arthritis

A
o	Reduce pain, stiffness, swelling and maintain mobility of joints
o	Education
o	Rest
o	Physiotherapy
o	Medication- analgesia, anti-inflammatories, DMARDS
o	Heat and cold
o	Support services
o	Assistance with daily living
19
Q

what is acute osteomyelitis

A

Acute infection of the bone (up to 6 weeks)

can be due to:
• Open fracture
• Infection due to surgery

20
Q

what is chronic osteomyelitis

A

Becomes chronic if it persists after 6-8 weeks

  • Sequestrum formation- dead bone
  • Requires long term antibiotic therapy
21
Q

what is osteoporosis

A
  • Long bone mass, and deterioration in the structure of bone
  • Diagnosis- bone mineral density measurement
  • Treatment- drugs to block bone resorption and to stimulate bone formation
  • Prevention- diet, lifestyle changes- increase in weight bearing exercise, stop smoking, calcium and vitamin D supplementation
  • Screening of susceptible people
22
Q

what is paget disease

A
  • Localised increase in bone formation and reabsorption
  • Bone replacement is rapid and chaotic, producing poor quality bone
    treated with NSAIDS, anti-inflammatory, calcitonin
23
Q

what is gout

A
  • Due to an elevation in serum uric acid levels
    o End-product of purine metabolism
  • Over production of purine, and decreased ability to excrete uric acid (as in chronic renal failure)
  • Uric acid crystals precipitate in the joint causing inflammation
    o Tophi- large hard nodules containing uric acid crystals (late stage disease)