WK5 Flashcards
Repair and regeneration have several important differences. One of the differences is that repair occurs in tissues that were made up of ________ , whereas regeneration occurs in tissues made up of __________.
- permanent cells 2. labile or stable cells
_____ collagen is the most common type of collagen found in skin, bone, tendon, and ligament.
Type 1
______ collagen is located in cartilage.
Type II
_______ collagen is located in pliable tissues like blood vessels, uterus, GI tract and skin
Type III
_____ collagen is located in basement membranes
Type IV
Wound healing contraction starts ______ days post wound, and eventually contracts up to ____ of the wound area.
- 2-3 days 2. 70%
What are the phases of wound healing and what are there approximate timeframes.
- Inflammation Phase: acute phase lasting only a few days
- Proliferative Phase: begins 48 hours after injury
3.Maturation Phase: can last up to two years
The goal of the maturation phase of wound healing is to increase the tensile strength of the scar. It is important to realize that a scar is only about _____ of the strength of originally intact skin.
- 80%
When is the proliferative phase of wound healing is complete?
when the wound is 100% resurfaced
What are the differences between healing with primary and secondary intention ?
In primary intention the cut is typically clean and sutured
In secondary intention wound with seperated edges which typically takes much longer during healing
What are the local and systemic factors that can influence healing ?
Local: type, size of the wound, the location of the wound, adequacy of vascular supply, temperature, and moisture
Systemic: circulatory and metabolic status, infection, diabetes, neoplasia, and nutritional levels
What are the differences between arterial and venous insufficiency ?
arterial insuffiency: punched out shape, pale granulation, deep, dry, loss of hair
venous insufficiency: irregular shape, red wound bed, shallow, copious,]
Decreased circulation from pressure leads to ulceration. This is typically caused by unrelieved pressure generally found over bony prominences. These wounds are staged according to the depth of tissue damage. The above characteristics describe which type of wound?
pressure ulcers
What are the differences between keloid scars and hypertrophic scars ?
Keloid Scars: growth of a scar beyond the confines of the original wound
Hypertrophic Scarring: scar stays within the confines of wound, often seen in burns
What kind of cells are in the kidneys, lungs, and liver, and which kind are in the heart ?
- stable cells 2. permanent cells