WK1: STRUCTURE, ORDER, FUNCTION Flashcards
what is molarity?
moles per litre solution
what is molality?
moles per kg solvent
what is osmolarity?
osmoses per litre solution
what is osmolality?
osmoses per kg solvent
hypotonic
lower osmotic pressure outside cell
hypertonic
higher osmotic pressure outside cell
isotonic
equal osmotic pressure inside and outside cell
what are the 3 properties of molecules?
hydrophobic, hydrophilic, amphiphilic
interstitial fluid
extracellular fluid outside blood vessels
plasma
extracellular fluid of blood
transcellular fluid
extracellular fluid in spaces e.g. brain ventricles, joint capsules, peritoneal cavity
intracellular fluid
water within cells
describe the plasma membrane
hydrophobic barrier
lipid soluble molecules can pass freely through lipid bilayer
polar molecules / ions etc. need specific membrane proteins
total osmolarity of solution =
sum of osmolality due to each constituents in solution
blood plasma osmolality
300 mOsmol kg-1
principal ions osmolality
280 mOsmol kg-1
glucose/small molecules osmolality
<10
proteins osmolality
<1
why do proteins have such a low osmolality?
their molecular mass is very high; per gram of protein, the osmotic pressure is lower compared to ions / glucose
what is osmotic pressure? what does it depend on?
the minimum pressure needed to prevent inward flow of water across semipermeable membrane. depends on number of particles present not chemical composition.
salts osmotic pressure?
2x molar concentration as salts dissociate into constituent ions
osmotic pressure equation?
osmotic pressure = MRT
osmotic pressure definition?
one gram mole of non-dissociating substance in 1kg of water exerts osmotic pressure of 1 ormolu
iso-osmotic
2 solutions are same osmolality; no net pressure as there is same osmotic pressure