WK1: STRUCTURE, ORDER, FUNCTION Flashcards

1
Q

what is molarity?

A

moles per litre solution

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2
Q

what is molality?

A

moles per kg solvent

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3
Q

what is osmolarity?

A

osmoses per litre solution

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4
Q

what is osmolality?

A

osmoses per kg solvent

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5
Q

hypotonic

A

lower osmotic pressure outside cell

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6
Q

hypertonic

A

higher osmotic pressure outside cell

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7
Q

isotonic

A

equal osmotic pressure inside and outside cell

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8
Q

what are the 3 properties of molecules?

A

hydrophobic, hydrophilic, amphiphilic

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9
Q

interstitial fluid

A

extracellular fluid outside blood vessels

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10
Q

plasma

A

extracellular fluid of blood

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11
Q

transcellular fluid

A

extracellular fluid in spaces e.g. brain ventricles, joint capsules, peritoneal cavity

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12
Q

intracellular fluid

A

water within cells

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13
Q

describe the plasma membrane

A

hydrophobic barrier
lipid soluble molecules can pass freely through lipid bilayer
polar molecules / ions etc. need specific membrane proteins

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14
Q

total osmolarity of solution =

A

sum of osmolality due to each constituents in solution

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15
Q

blood plasma osmolality

A

300 mOsmol kg-1

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16
Q

principal ions osmolality

A

280 mOsmol kg-1

17
Q

glucose/small molecules osmolality

A

<10

18
Q

proteins osmolality

A

<1

19
Q

why do proteins have such a low osmolality?

A

their molecular mass is very high; per gram of protein, the osmotic pressure is lower compared to ions / glucose

20
Q

what is osmotic pressure? what does it depend on?

A

the minimum pressure needed to prevent inward flow of water across semipermeable membrane. depends on number of particles present not chemical composition.

21
Q

salts osmotic pressure?

A

2x molar concentration as salts dissociate into constituent ions

22
Q

osmotic pressure equation?

A

osmotic pressure = MRT

23
Q

osmotic pressure definition?

A

one gram mole of non-dissociating substance in 1kg of water exerts osmotic pressure of 1 ormolu

24
Q

iso-osmotic

A

2 solutions are same osmolality; no net pressure as there is same osmotic pressure

25
Q

iso-tonic

A

no pressure change between intra and extracellular volume. no net fluid movement.

26
Q

if isotonic, then also..

A

isosmotic. not all isosmotic solutions are isotonic though!

27
Q

why is blood diluted in 0.9% NaCl?

A

RBCs are surrounded by an isotonic environment (plasma)

28
Q

RBC in isotonic solution?

A

no change

29
Q

RBC in hypotonic solution?

A

cell bursts

30
Q

RBC in hypertonic solution?

A

cell shrivels/crenates