WK1: STRUCTURE, ORDER, FUNCTION Flashcards

1
Q

what is molarity?

A

moles per litre solution

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2
Q

what is molality?

A

moles per kg solvent

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3
Q

what is osmolarity?

A

osmoses per litre solution

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4
Q

what is osmolality?

A

osmoses per kg solvent

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5
Q

hypotonic

A

lower osmotic pressure outside cell

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6
Q

hypertonic

A

higher osmotic pressure outside cell

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7
Q

isotonic

A

equal osmotic pressure inside and outside cell

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8
Q

what are the 3 properties of molecules?

A

hydrophobic, hydrophilic, amphiphilic

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9
Q

interstitial fluid

A

extracellular fluid outside blood vessels

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10
Q

plasma

A

extracellular fluid of blood

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11
Q

transcellular fluid

A

extracellular fluid in spaces e.g. brain ventricles, joint capsules, peritoneal cavity

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12
Q

intracellular fluid

A

water within cells

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13
Q

describe the plasma membrane

A

hydrophobic barrier
lipid soluble molecules can pass freely through lipid bilayer
polar molecules / ions etc. need specific membrane proteins

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14
Q

total osmolarity of solution =

A

sum of osmolality due to each constituents in solution

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15
Q

blood plasma osmolality

A

300 mOsmol kg-1

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16
Q

principal ions osmolality

A

280 mOsmol kg-1

17
Q

glucose/small molecules osmolality

18
Q

proteins osmolality

19
Q

why do proteins have such a low osmolality?

A

their molecular mass is very high; per gram of protein, the osmotic pressure is lower compared to ions / glucose

20
Q

what is osmotic pressure? what does it depend on?

A

the minimum pressure needed to prevent inward flow of water across semipermeable membrane. depends on number of particles present not chemical composition.

21
Q

salts osmotic pressure?

A

2x molar concentration as salts dissociate into constituent ions

22
Q

osmotic pressure equation?

A

osmotic pressure = MRT

23
Q

osmotic pressure definition?

A

one gram mole of non-dissociating substance in 1kg of water exerts osmotic pressure of 1 ormolu

24
Q

iso-osmotic

A

2 solutions are same osmolality; no net pressure as there is same osmotic pressure

25
iso-tonic
no pressure change between intra and extracellular volume. no net fluid movement.
26
if isotonic, then also..
isosmotic. not all isosmotic solutions are isotonic though!
27
why is blood diluted in 0.9% NaCl?
RBCs are surrounded by an isotonic environment (plasma)
28
RBC in isotonic solution?
no change
29
RBC in hypotonic solution?
cell bursts
30
RBC in hypertonic solution?
cell shrivels/crenates