WK 13: 7 GUIDING PRINCIPLES

Question 1

Evaluation of a diagnostic or therapeutic intervention leading to health improvement while increasing knowledge

Answer 1

Social or scientific value

Question 2

Study should present with a scientifically sound design, ensuring research outcomes with ACCURATE AND REPRODUCIBLE endpoints

Answer 2

scientific validity

Question 3

research subjects should be selected through fair inclusion and exclusion criteria

Answer 3

fair subject selection

Question 4

risks to participants should be minimized while benefits should be maximized

Answer 4

favorable risk/ benefit ratio

Question 5

evaluation of adherence to ethical standards by full committee of unaffiliated individuals with expertise

Answer 5

independent review

Question 6

subjects must be accurately INFORMED OF BENEFITS, HARMS AND ALTERNATIVES TO THE PROPOSED RESEARCH

Answer 6

Informed consent

Question 7

Individuals must be respectfully treated thoughout the study

Answer 7

respect for enrolled participants