Whole Blood Flashcards
Primary component, “mother bag”
whole blood
Components that can be made with whole blood
RBC
WBC
plasma proteins
platelet
cryoprecipitate
Indications of Whole Blood
active bleeding
hemorrhagic shock
exchange transfusion
Shelf Life: Heparin
2 days
Shelf Life: ACD, CPD, CP2D
21 days
Shelf Life: CPD-A1
35 days
Shelf Life: Adsol (AS1), Nutricel (AS3), Optisol (AS5)
42 days
Storage Temperature
1-6 deg C (ref temp)
ice water (transport)
no longer viable after 24 hrs
WBC and platelets
decreased after 2 days of storage
Labile Factors (FV, VIII)
Immediate Effect after administration of 1 unit
↑3% hematocrit, for each 1 unit of whole blood
associated problems encountered after transfusion of whole blood
circulatory overload
whole blood is indicated for patients who needs
oxygen carrying capacity
volume expansion
px doesn’t need volume expansion, thus it needs to replenish oxygen carrying capacity. what would you administer?
4 packed RBC
Component of RBC Additive Solution
AS1
AS3
AS5
Contents of RBC Additive Solution
Mannitol
Adenine
Glucose
Saline
no exposure to air
closed system
component is automatically labeled as “expires in 24hrs time” or “expired”
open system
most commonly used anticoagulant additive solution for blood bags
CPDA1
most commonly used anticoagulant additive solution for apheresis procedure
ACD
