White Blood Cells (Leukocytes) Flashcards
White blood cells (WBCs) are also called
leukocytes
leukocytes are
immune system cells
how many types of leukocytes are there typically
5
difference between leukocytes and red blood cells (RBCs)
leukocytes have nuclei RBCs do not
leukocyte nuclei have
extensions called lobes
what distinguishes different types of WBCs
shape of the nucleus number of lobes appearance and color of granules
Cell organelles form
granules
what is more easily seen in some types of leukocytes
granules
criteria to distinguish and quantify WBCs in the lab
Wright Stain Leukocytes in blood Measurements of leukocytes
Wright Stain
combined from Methylene Blue and Eosin used to treat prepared slides of blood some WBCs are named based on their affinity to its components
Leukocytes are nearly colorless. True or False
colorless
Methylene Blue, acid or base
alkaline (basic)
Eosin, acid or base
acidic red
What two groups are leukocytes are separated into?
Agranulocytes- generally hard to see granules
Granulocytes- easily seen granules
Agranulocytes
typically hard to see granules
lymphocytes monocytes
lymphocytes
smallest of WBCs can not see granules nuclei are spherical and fill them difficult to see a thin rim of cytoplasm

what leukocyte are these

lymphocytes
monocytes
largest leukocytes
can’t see granules
can see clear to light-blue cytoplasm surrounding the nucleus
nucleus is bi-lobed
transform into macrophages which enter other body tissues

what leukocyte is this

monocytes
granulocytes
can see granules
neutrophils
eosinophils
basophils
neutrophils
have nuclei with several lobes, typically 3-6
equal attraction to components of wright stain
granules are pale lavender

what leukocyte is this

neutrophils
eosinophils
affinity for eosin in Wright Stain
granules are pink-red

what leukocytes are these

eosinophils
basophils
affinity for Methylene Blue (basic) in Wright Stain
large, chunky, dark blue-purple granules
so dark and large it can be hard to see the nucleus

what leukocyte is this

basophil
what is used to measure leukocytes
differential WBC count
number of WBCs per unit volume of blood
differential WBC count
compares percentages of each of the 5 leukocytes to what is expected in healthy blood
percentage of neutrophils in healthy blood
normally 50-70%
percentage of lymphocytes in healthy blood
25-35%
percentage of monocytes in healthy blood
4-6%
percentage of eosinophils in healthy blood
1-3%
percentage of basophils in healthy blood
less than 1%
what do differentiating percentages of leukocytes from healthy blood provide
diagnostic info based on different functions of WBCs
what elevates neutrophils
bacterial infection
lymphocyte rapid increase is associated with
antibody production
elevated eosinophils can indicate
parasitic worm infection
more numerous basophils are associated with
chronic inflammation
what are the only leukocytes with more than 2 lobes on its nucleus
neutrophils
what are the most common leukocytes (agranulocytes and granulocytes)
lymphocytes- agranulocytes
neutrophils- granulocytes
What leukocytes are agranulocytes
lymphocytes
monocytes
what leukocytes are granulocytes
neutrophils
eosinophils
basophils