White Blood Cells (Leukocytes) Flashcards

1
Q

White blood cells (WBCs) are also called

A

leukocytes

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2
Q

leukocytes are

A

immune system cells

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3
Q

how many types of leukocytes are there typically

A

5

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4
Q

difference between leukocytes and red blood cells (RBCs)

A

leukocytes have nuclei RBCs do not

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5
Q

leukocyte nuclei have

A

extensions called lobes

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6
Q

what distinguishes different types of WBCs

A

shape of the nucleus number of lobes appearance and color of granules

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7
Q

Cell organelles form

A

granules

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8
Q

what is more easily seen in some types of leukocytes

A

granules

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9
Q

criteria to distinguish and quantify WBCs in the lab

A

Wright Stain Leukocytes in blood Measurements of leukocytes

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10
Q

Wright Stain

A

combined from Methylene Blue and Eosin used to treat prepared slides of blood some WBCs are named based on their affinity to its components

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11
Q

Leukocytes are nearly colorless. True or False

A

colorless

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12
Q

Methylene Blue, acid or base

A

alkaline (basic)

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13
Q

Eosin, acid or base

A

acidic red

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14
Q

What two groups are leukocytes are separated into?

A

Agranulocytes- generally hard to see granules

Granulocytes- easily seen granules

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15
Q

Agranulocytes

A

typically hard to see granules

lymphocytes monocytes

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16
Q

lymphocytes

A

smallest of WBCs can not see granules nuclei are spherical and fill them difficult to see a thin rim of cytoplasm

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17
Q

what leukocyte are these

A

lymphocytes

18
Q

monocytes

A

largest leukocytes

can’t see granules

can see clear to light-blue cytoplasm surrounding the nucleus

nucleus is bi-lobed

transform into macrophages which enter other body tissues

19
Q

what leukocyte is this

20
Q

granulocytes

A

can see granules

neutrophils

eosinophils

basophils

21
Q

neutrophils

A

have nuclei with several lobes, typically 3-6

equal attraction to components of wright stain

granules are pale lavender

22
Q

what leukocyte is this

A

neutrophils

23
Q

eosinophils

A

affinity for eosin in Wright Stain

granules are pink-red

24
Q

what leukocytes are these

A

eosinophils

25
basophils
affinity for Methylene Blue (basic) in Wright Stain large, chunky, dark blue-purple granules so dark and large it can be hard to see the nucleus
26
what leukocyte is this
basophil
27
what is used to measure leukocytes
differential WBC count number of WBCs per unit volume of blood
28
differential WBC count
compares percentages of each of the 5 leukocytes to what is expected in healthy blood
29
percentage of neutrophils in healthy blood
normally 50-70%
30
percentage of lymphocytes in healthy blood
25-35%
31
percentage of monocytes in healthy blood
4-6%
32
percentage of eosinophils in healthy blood
1-3%
33
percentage of basophils in healthy blood
less than 1%
34
what do differentiating percentages of leukocytes from healthy blood provide
diagnostic info based on different functions of WBCs
35
what elevates neutrophils
bacterial infection
36
lymphocyte rapid increase is associated with
antibody production
37
elevated eosinophils can indicate
parasitic worm infection
38
more numerous basophils are associated with
chronic inflammation
39
what are the only leukocytes with more than 2 lobes on its nucleus
neutrophils
40
what are the most common leukocytes (agranulocytes and granulocytes)
lymphocytes- agranulocytes neutrophils- granulocytes
41
What leukocytes are agranulocytes
lymphocytes monocytes
42
what leukocytes are granulocytes
neutrophils eosinophils basophils