White Blood Cells (Leukocytes) Flashcards

1
Q

White blood cells (WBCs) are also called

A

leukocytes

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2
Q

leukocytes are

A

immune system cells

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3
Q

how many types of leukocytes are there typically

A

5

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4
Q

difference between leukocytes and red blood cells (RBCs)

A

leukocytes have nuclei RBCs do not

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5
Q

leukocyte nuclei have

A

extensions called lobes

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6
Q

what distinguishes different types of WBCs

A

shape of the nucleus number of lobes appearance and color of granules

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7
Q

Cell organelles form

A

granules

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8
Q

what is more easily seen in some types of leukocytes

A

granules

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9
Q

criteria to distinguish and quantify WBCs in the lab

A

Wright Stain Leukocytes in blood Measurements of leukocytes

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10
Q

Wright Stain

A

combined from Methylene Blue and Eosin used to treat prepared slides of blood some WBCs are named based on their affinity to its components

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11
Q

Leukocytes are nearly colorless. True or False

A

colorless

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12
Q

Methylene Blue, acid or base

A

alkaline (basic)

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13
Q

Eosin, acid or base

A

acidic red

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14
Q

What two groups are leukocytes are separated into?

A

Agranulocytes- generally hard to see granules

Granulocytes- easily seen granules

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15
Q

Agranulocytes

A

typically hard to see granules

lymphocytes monocytes

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16
Q

lymphocytes

A

smallest of WBCs can not see granules nuclei are spherical and fill them difficult to see a thin rim of cytoplasm

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17
Q

what leukocyte are these

A

lymphocytes

18
Q

monocytes

A

largest leukocytes

can’t see granules

can see clear to light-blue cytoplasm surrounding the nucleus

nucleus is bi-lobed

transform into macrophages which enter other body tissues

19
Q

what leukocyte is this

A

monocytes

20
Q

granulocytes

A

can see granules

neutrophils

eosinophils

basophils

21
Q

neutrophils

A

have nuclei with several lobes, typically 3-6

equal attraction to components of wright stain

granules are pale lavender

22
Q

what leukocyte is this

A

neutrophils

23
Q

eosinophils

A

affinity for eosin in Wright Stain

granules are pink-red

24
Q

what leukocytes are these

A

eosinophils

25
Q

basophils

A

affinity for Methylene Blue (basic) in Wright Stain

large, chunky, dark blue-purple granules

so dark and large it can be hard to see the nucleus

26
Q

what leukocyte is this

A

basophil

27
Q

what is used to measure leukocytes

A

differential WBC count

number of WBCs per unit volume of blood

28
Q

differential WBC count

A

compares percentages of each of the 5 leukocytes to what is expected in healthy blood

29
Q

percentage of neutrophils in healthy blood

A

normally 50-70%

30
Q

percentage of lymphocytes in healthy blood

A

25-35%

31
Q

percentage of monocytes in healthy blood

A

4-6%

32
Q

percentage of eosinophils in healthy blood

A

1-3%

33
Q

percentage of basophils in healthy blood

A

less than 1%

34
Q

what do differentiating percentages of leukocytes from healthy blood provide

A

diagnostic info based on different functions of WBCs

35
Q

what elevates neutrophils

A

bacterial infection

36
Q

lymphocyte rapid increase is associated with

A

antibody production

37
Q

elevated eosinophils can indicate

A

parasitic worm infection

38
Q

more numerous basophils are associated with

A

chronic inflammation

39
Q

what are the only leukocytes with more than 2 lobes on its nucleus

A

neutrophils

40
Q

what are the most common leukocytes (agranulocytes and granulocytes)

A

lymphocytes- agranulocytes

neutrophils- granulocytes

41
Q

What leukocytes are agranulocytes

A

lymphocytes

monocytes

42
Q

what leukocytes are granulocytes

A

neutrophils

eosinophils

basophils