Where Anaesthetics Operate

Question 1

Anaesthetics act in regions of the _

Answer 1

Synapse

Question 2

Conduction of nerve impulses along the axon is achieved by _ of ions through protein channels

Answer 2

Rapid entry and exit

Question 3

Rapid entry and exit of ions through protein channel causes a small _ that spreads down nerve

Answer 3

Electrical current

Question 4

Because different types of molecules can all cause anesthesia, it is thought that _ may be involved

Answer 4

Several molecular sites

Question 5

Early studies suggest that site of Anaesthetic drug is within _ of cell

Answer 5

Membrane

Question 6

Site within membrane because potency of inhaled anaesthetic drug proportional to their solubility in _

Answer 6

Oil

(Oil closely resembles lipid)

Question 7

Assumption is that by _ anaesthetics may change properties of membrane

Answer 7

Inserting themselves into lipid bilayer

Question 8

Further studies suggested that anaesthetic drugs in lipid bilayer cause membrane to _

Answer 8

Expand

Question 9

Expanding membrane causes _

Answer 9

Pores to close