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Pharmacology drugs > what would you prescribe for... > Flashcards

what would you prescribe for... Flashcards

1
Q

urinary incontinence

A

anitmuscarinics (bethanachol/ureocholine)

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2
Q

MOA antimuscarinics

A

parasympathetic stimulation causes bladder spasm

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3
Q

Contraindications for antimuscarinics

A

GI obstruction, asthma, parkinsons, PUD

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4
Q

ADR antimuscarinics

A

HOTN, tachy, cramping, diarrhea

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5
Q

Acute causes of BPH

A

antiarrhytmics, antihypertensives, OTC cold meds

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6
Q

Chronic cause of BPH

A

weak detrusor

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7
Q

treatment of BPH

A

alpha blockers, PDE5i, 5 alpha reductase inhibitors

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8
Q

Name the alpha blockers

A

Doxazosin (Cardura), Tamsulosin (Flomax)

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9
Q

Name the 5 alpha reductase i

A

dutasteride (Avodart), finasteride (proscar)

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10
Q

name the PDE5i

A

cialis (tadalafil)

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11
Q

which alpha blockers work on all three alpha receptors

A

doxazosin, terazosin, alfuzosin

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12
Q

which alpha blocker works only on BV and would be good in HTN

A

silozosin

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13
Q

What alpha blocker is selective for alpha A and D?

A

tamsulosin

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14
Q

what is something to look out for with prescribing alpha blockers along with other drugs?

A

interactions!!

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15
Q

Do alpha blockers work?

A

the decrease LUTS, no long term benefit

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16
Q

MOA of 5 alpha reductase i

A

decrease DHT levels

17
Q

benefits of finasteride/dutasteride?

A

finasteride has a faster onset and dutasteride has a longer half life

18
Q

how is the PSA affected with 5 alpha reductase i?

A

after 6 months of therapy the new PSA baseline is cut 50%

19
Q

ADR of dutasteride and finasteride?

A

impotence, high TSH, decreased libido

20
Q

Treatment for erectile dyfunction

A

PDE5i, yohimbine, enzyte, vasotran auctum

21
Q

name the PDE5i

A

tadalafil (cialis), sildenafil (Viagra)

22
Q

MOA of PDE5i

A

increase cGMP

23
Q

ADR of sildenafil

A

PDE6 attack causes blue vision

24
Q

ADR of tadalafil

A

PDE11 attack causes back pain

25
Q

ADR of PDE5i in general

A

photosensitivity, HA, flushing

26
Q

alternative treatment use of PDE5i

A

PAH

27
Q

contraindications for PDE5i

A

nitrate use, also using alpha blockers (add PDE5i on when alpha blockers are stable)

28
Q

erection lasting more than 4 hours should get

A

ephedrine, NE, aspiration

29
Q

MOA of yohimbine

A

alpha 2 blocker

30
Q

ADR yohimbine

A

HTN, nervousness, tremor

31
Q

MOA of vasotran auctim

A

produced NO

32
Q

components of vasotram auctum

A

lL-arginine, yohimbine, ginseng, methyl nicotinate

33
Q

components of enzyte

A

ginkgo, saw palmetto, ginseng, yohimbine, mala, tribulus terrestris

34
Q

treatment of female sexual dysfxn

A

local estrogens, testosterone creams, sildenafil

35
Q

treatment of dyspareunia

A

ospemifene (estrogen receptor modulator)

36
Q

ADr ospemifine

A

flushing

Pharmacology drugs (3 decks)

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