what is the adrenal cortex Flashcards

1
Q

what is the name given to the outer layer of the adrenal gland

A

adrenal cortex

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2
Q

describe adrenal gland

A

one of a pair of glands above the kidneys which release adrenaline and corticoids

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3
Q

what is adrenaline

A

hormone released by adrenal glands which stimulates fight or flight response

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4
Q

what is the adrenal medulla

A

inner layer of the adrenal gland

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5
Q

what is the difference between the adrenal cortex and meddulla

A

medulla- inner layer of adrenal gland

cortex- outer layer

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6
Q

adrenal medulla and cortex are well vascularised what does this mean

A

well supplied with blood vessels which allows hormones to be directed into blood

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7
Q

what are the three layers of cells in the adrenal cortex

A

zona glomerulosa- outer layer secretes aldosterone

zona fasciculata- middle layer, secretes cortisol

zona reticularis- inner layer makes molecules used to make sex hormones

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8
Q

what does the zona glomerulosa do

A

outer most layer of the adrenal cortex
secretes mineralocroticoids, ALDOSTERONE

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9
Q

what does the zona fasciculata do

A

middle layer of the adrenal cortex
produces glucocorticoids such as CORTISOL

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10
Q

what does the zona reticularis do

A

inner layer of adrenal cortex,
secretes molecules used to make sex hormones

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11
Q

what hormones does the adrenal medulla secrete

A

adrenaline
noradrenaline

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12
Q

what molecule is used by the adrenal cortex to produce hormones

A

adrenal cortex uses cholestrol to produce hormones

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13
Q

where is cholestrol located in the membrane

A

sits in the middle of the hydrophobic part of the bilayer

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14
Q

what type of hormone does cholestrol help produce in the adrenal cortex

A

steroid hormones

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15
Q

describe the action of steroid hormones

A

steroid hormones pass through plasma membrane of target cell

steroid hormone binds to receptor in cytoplasm

receptor steroid hormone complex enters nucleus and binds to receptor on chromosomal material

stimulates production of mrna which codes for protein production

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16
Q

can steroid hormones pass through plasma membrane

A

yes
non steroid cant

17
Q

what is the role of aldosterone from zona glomerulosa from adrenal cortex

A

helps control sodium and potassium conc in blood

maintain blood pressure.

acts on distal tubules and collecting ducts in kidney increasing absorption of sodium ions and decrease absorption of potassium.

18
Q

what does cortisol do from zona fasiculata from adrenal cortex

A

controls metabolism of carbs, fats, proteins in liver
cotrisol is released response to low glucose conc.
stimulates production of glucose from glycogen.

19
Q

is adernaline polar or non polar

A

polar

20
Q

what amino acid is adrenaline derived from

A

tyrosine

21
Q

if adrenaline is polar what does this mean about its entry in the phospholipid membrane

A

it cant enter plasma membrane as it is polar .
must be detected by specialised receptors

22
Q

if lots of tissues have adrenaline receptors what does this mean

A

effect of adrenaline is widespread

23
Q

what are the effects of adrenaline

A

increase heart rate

dilate pupils

stimulate conversion of glycogen to glucose

initiate vasoconstriction to raise blood pressure

inhibit gut action

24
Q

what does the fight or flight response mean

A

prepare body to either defend itself or run away to escape danger