West Nile Virus Flashcards

1
Q

What is the leading cause of domestically acquired arboviral disease in the U.S?

A

West Nile Virus

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2
Q

What are predisposing factors of West Nile Virus?

A

1) Outdoor Activities during SPRING and SUMMER
2) Mosquito Bites

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3
Q

How is West Nile Virus transmitted?

A

1) Culex Mosquito
2) Blood Transfusion
3) Organ Donation
4) Mother to Child transmission

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4
Q

What mosquito is responsible for transmitting West Nile Virus?

A

Culex Mosquito

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5
Q

What is the incubation period for West Nile Virus?

A

2-6 days

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6
Q

Is West Nile Virus a reportable disease?

A

Yes

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7
Q

What type of West Nile Virus is lethal?

A

Neuroinvasive

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8
Q

When do West Nile Virus outbreaks typically occur?

A

Spring/Summer

Mid July to Early September

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9
Q

Why do elevated temperatures & rainfall correlate with increased WNV transmission & infection?

A

The warmer & hotter it is, the more mosquitos will breed

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10
Q

What are considerd “Dead End Hosts” with West Nile Virus?

A

Humans and Horses

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11
Q

Is a patient infected with west nile virus infectious to others aboard the ship?

A

Nah, Humans are Dead End Hosts

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12
Q

Mosquitoes become infected with west nile virus when they feed on ______________.

A

Infected Birds

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13
Q

When should west nile virus be considered?

A

In any febrile patient or acute neurologic illness with recent exposure to mosquitoes during the summer months in WNV endemic areas.

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14
Q

An acute systemic febrile illness that may be accompanied by:

1) Headache, weakness, myalgia, or arthralgia
2) Gastrointestinal symptoms
3) Transient (Come and Go) maculopapular rash

A

West Nile Virus

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15
Q

Neuroinvasive West Nile Virus typically manifests as ___________, ____________, or _____________.

A

1) WNV Meningitis
2) WNV Encephalitis
3) ANV Acute Flaccid Paralysis

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16
Q

What neuroinvasive manifestation of west nile virus presents with fever, headache, and nuchal rigidity.

A

WNV Meningitis

17
Q

What neuroinvasive manifestation of west nile virus presents with fever and altered mental status, seizures, focal neurologic deficits, or movement disorders such as tremor or Parkinsonism.

A

WNV Encephalitis

18
Q

What neuroinvasive manifestation of west nile virus presents with respiratory paralysis requiring mechanical ventilation, isolated limb paresis or paralysis and can occur without fever or apparent viral prodrome.

A

WNV Acute Flaccid Paralysis

19
Q

How is West Nile Virus Diagnosed?

A

Identifying IgM antibodies in the serum or Cerebral Spinal Fluid with ELISA

20
Q

Mumps, HSV, Poliovirus, Measles, and Pertussis are differential diagnoses for what infectious disease?

A

West Nile Virus

21
Q

What is the first line management protocol for West Nile Virus?

A

Vigorous supportive measures:

1) Severe meningeal symptoms- Pain control, Antiemetics, and Rehydration
2) Encephalitis symptoms- Monitor for seizures due to increased inracranial pressure. Monitor Airway.
3) Poliomyelitis Symptoms- Monitor Airway
4) Ventilator support if respiratory failure

22
Q

What is the disposition for West Nile Virus?

A

MEDEVAC if signs of encephalitis, meningitis, or paralysis.

23
Q

What are the prevention methods for West Nile Virus?

A

1) Mosquito Control
2) Protective measures (Repellents, Long sleeve shirts and pants, limit outdoor exposure during the night)
3) Screening blood and organ donors
4) Air conditioning, window and door screens, reducing breeding sites

24
Q

How long can the fatigue, malaise, and weakness be present for a patient with non-neuroinvasive West Nile Virus?

A

Weeks to Months

25
Q

What type of Neuroinvasive West Nile Virus has the lowest fatality rate?

A

West Nile Virus Meningitis

26
Q

What types of Neuroinvasive West Nile Virus may have residual neurologic deficits?

A

WNV Encephalitis

WNV Poliomyelitis

27
Q
A