Wernicke Encephalopathy Flashcards
1
Q
What is the underlying pathophysiology of wernicke encephalopathy
A
Thiamine (B1) deficiency
2
Q
Treatment for Wernicke Encephalopathy?
A
IV/IM Pabrinex (Thiamine)
Give oral supplementation of thiamine once patient no longer at risk
3
Q
Classical triad for Wernicke Encephalopathy?
A
Confusion
Ataxia
Ophthalmoplegia
4
Q
5 causes of Wernicke Encephalopathy?
A
Chronic malnutrition Chronic alcoholism Excessive vomiting - GI malignancy - Hyperemesis Gravidarum - Psychiatric disorders i.e anorexia - Chemotherapy
5
Q
Irreversible consequence of Wernicke Encephalopathy
A
Wernicke Korsakoff Syndrome
6
Q
2 features of mental state examination in Korsakoff syndrome?
A
Apathy
Loss of insight
7
Q
3 features of Korsakoff syndrome?
A
Retrograde amnesia
Anterograde amnesia
Confabulation
