Wellington mock Flashcards

1
Q

Rate limiting step glycolytic pathway

A

phosphofructokinase

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2
Q

Rate limiting step electron transport chain

A

cytochrome oxidase

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3
Q

Reversible ischaemic injury is characterised by

A

potassium efflux from cells due with failure of the sodium pump

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4
Q

Peak action salbutamol

A

15-30m
duration 4-6h
Half life 4h

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5
Q

Peak effect ipratropium

A

30-60m
duration 3-6
T1/2 1.5h

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6
Q

Clonidine withdrawal

A

tachycardia, restlessness, insomnia, headache, nausea, vomiting, palpitations, cardiac arrhythmia, and hypertensive encephalopathy

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7
Q

Cause of nutmeg liver

A

hepatic hypoperfusion

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8
Q

Genetic abnormality casing CF

A

deletions

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9
Q

Epicardial arteries

A

another name for coronary arteries

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10
Q

Successful immune response to HIV during the acute phase

A

development of CD8+ virus specific cytotoxic cells

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11
Q

Speed in AV node

A

0.05m/s

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12
Q

Cause of visceral pain

A

distention

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13
Q

Smallest A nerve fibre

A

delta

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14
Q

Hep B immunisation schedule

A

0, 1, 6m

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15
Q

Angiotensin II AT1 effect on

A

arterioles

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16
Q

2nd generation cephalosporin coverage

A

very active against gram positive cocci with added gram negative and klebsiella coverage

17
Q

Hydrogen ion secretion in the distal tubules and collecting ducts is controlled by

A

Aldosterone control of ATP driven H+ pump

18
Q

Apical membrane

A

faces lumen

19
Q

Mechanism of spironalactone

A

on mineralocorticoid receptor (not directly on ENaC)

20
Q

ENaC blocker

A

Amiloride

21
Q

Gestation ectopic pregnancy rupture

A

6 weeks

22
Q

Urine threshold for gucose

A

Threshold for urine 200
TMg 300 women 375 men (transport max)

23
Q

Glucose maximally absorbed GI

A

jejenum

24
Q

Weak acid definition

A

A neutral molecule that can reversibly dissociate an anion with a proton

25
Q

Weak base definition

A

one which doesn’t convert fully into hydroxide ions in solution (doesn’t fully dissociate)

26
Q

Synaptic vesicle sizes

A

Small clear synaptic vesicles - Neurotransmitters e.g. acetylcholine
Small dense core - catecholamines
Large dense-core vesicles - neuropeptides

27
Q

Graves ABs

A

anti-TSH receptor antibodies

28
Q

Thyroid peroxidase antibodies

A

hashimotos

29
Q

Thyroglobulin antibodies

A

associated cancer +- hashimotos

30
Q

Mechanism TCAs

A

block amine reuptake pumps at presynaptic nerve endings

31
Q

Hb dissociation curve in excercise

A

shifts to the right in tissues and left in lungs

32
Q
A