EMCQ practice 1

Question 1

Last part of heart to depolarise

Answer 1

pulmonary conus
uppermost part septum
posterobasal LV

Question 2

Length of heart contractile response

Answer 2

1.5x action potential

Question 3

Phases absolute refractory period

Answer 3

0 1 2 and first half 3 until -50

Question 4

Only nerve in afferent and efferent swallow

Answer 4

V

Question 5

% water in colon reabsorbed

Answer 5

90

Question 6

Omeprazole pK

Answer 6

VD 0.4, 95% PB, F0.4-0.6
T12 <1h, completely metabolised liver

Question 7

Milrinone

Answer 7

PDE3 inhibitor
good for R heart failure
vasodilates and inotrope

Question 8

Things increasing and reducing digoxin absorbtion

Answer 8

increased by erythromycin
decreased by antacids

Question 9

Digoxin pK

Answer 9

F0.7
T1/2 40
VD high
25% PB
only 20% metabolised (OK in hepatic failure)

Question 10

Adenosine effect enhanced by

Answer 10

dipyridamole
(inhibited caffeine, theophyline)

Question 11

Treatment kawasaki

Answer 11

IVIG
aspirin

Question 12

Aminoglycoside antimicrobial resistance via

Answer 12

enzyme inhibition

Question 13

Cinchonism

Answer 13

abdo pain, d and v, tinnitus, altered vision
due to (hydroxy)chloroquine)

Question 14

AmpCbetalactamase

Answer 14

hydrolyses penicillin and cephalosporins

Question 15

Carbapenemase

Answer 15

hydrolyses penicillin, cephalosporins, monobactams and carbapenems

Question 16

Penicillin G action

Answer 16

+ve, -ve cocci, non beta lactamase anaerobes

Question 17

Cytokine signalling pathway

Answer 17

JAK stat

Question 18

GPIb vs GP IIbIIIa

Answer 18

Ib - adhesion to collagen with vWF
IIB - aggregation with plt and fibrinogen

Question 19

Prostacyclin and NO effect on plt

Answer 19

inhibit adhesion

Question 20

Pneumocytsis jirovecci diagnosis

Answer 20

silver staining

For all fungi and legionella

Question 21

Vascular dementia

Answer 21

bilateral grey and white matter lesions

Question 22

VIP on bronchial smooth muscle

Answer 22

relaxes

Question 23

Mycotic aneurysm

Answer 23

from infection
abdominal and thoracic aorta
femoral
cerebral - anterior circulation, causes infarct

Question 24

Innervation politeus

Answer 24

tibial nerve

Question 25

left temporal lobe lesion

Answer 25

upper right homonymous quadrantonopia

Question 26

suprapatellar bursa

Answer 26

connects with knee

Question 27

Index finger dermatomes

Answer 27

palmar C6
dorsal C7

Question 28

Medial forearm dermatome

Answer 28

T1

Question 29

Cause berry aneurysm

Answer 29

degeneration tunica media

Question 30

Blood smear haemolytic anaemia

Answer 30

reticulocytes
heinz bodies
spherocytes
fragmented RBC

Question 31

% pulmonary emboli causing infarction

Answer 31

5-15%

Question 32

Most common site of lung met

Answer 32

adrenal

Question 33

Infraorbital nerve location

Answer 33

orbital floor, injured if # to roof of maxillary sinus

Question 34

% People mobile gallbladder

Answer 34

4