EMCQ practice 1 Flashcards

1
Q

Last part of heart to depolarise

A

pulmonary conus
uppermost part septum
posterobasal LV

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2
Q

Length of heart contractile response

A

1.5x action potential

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3
Q

Phases absolute refractory period

A

0 1 2 and first half 3 until -50

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4
Q

Only nerve in afferent and efferent swallow

A

V

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5
Q

% water in colon reabsorbed

A

90

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6
Q

Omeprazole pK

A

VD 0.4, 95% PB, F0.4-0.6
T12 <1h, completely metabolised liver

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7
Q

Milrinone

A

PDE3 inhibitor
good for R heart failure
vasodilates and inotrope

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8
Q

Things increasing and reducing digoxin absorbtion

A

increased by erythromycin
decreased by antacids

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9
Q

Digoxin pK

A

F0.7
T1/2 40
VD high
25% PB
only 20% metabolised (OK in hepatic failure)

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10
Q

Adenosine effect enhanced by

A

dipyridamole
(inhibited caffeine, theophyline)

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11
Q

Treatment kawasaki

A

IVIG
aspirin

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12
Q

Aminoglycoside antimicrobial resistance via

A

enzyme inhibition

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13
Q

Cinchonism

A

abdo pain, d and v, tinnitus, altered vision
due to (hydroxy)chloroquine)

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14
Q

AmpCbetalactamase

A

hydrolyses penicillin and cephalosporins

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15
Q

Carbapenemase

A

hydrolyses penicillin, cephalosporins, monobactams and carbapenems

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16
Q

Penicillin G action

A

+ve, -ve cocci, non beta lactamase anaerobes

17
Q

Cytokine signalling pathway

A

JAK stat

18
Q

GPIb vs GP IIbIIIa

A

Ib - adhesion to collagen with vWF
IIB - aggregation with plt and fibrinogen

19
Q

Prostacyclin and NO effect on plt

A

inhibit adhesion

20
Q

Pneumocytsis jirovecci diagnosis

A

silver staining

For all fungi and legionella

21
Q

Vascular dementia

A

bilateral grey and white matter lesions

22
Q

VIP on bronchial smooth muscle

A

relaxes

23
Q

Mycotic aneurysm

A

from infection
abdominal and thoracic aorta
femoral
cerebral - anterior circulation, causes infarct

24
Q

Innervation politeus

A

tibial nerve

25
Q

left temporal lobe lesion

A

upper right homonymous quadrantonopia

26
Q

suprapatellar bursa

A

connects with knee

27
Q

Index finger dermatomes

A

palmar C6
dorsal C7

28
Q

Medial forearm dermatome

A

T1

29
Q

Cause berry aneurysm

A

degeneration tunica media

30
Q

Blood smear haemolytic anaemia

A

reticulocytes
heinz bodies
spherocytes
fragmented RBC

31
Q

% pulmonary emboli causing infarction

A

5-15%

32
Q

Most common site of lung met

A

adrenal

33
Q

Infraorbital nerve location

A

orbital floor, injured if # to roof of maxillary sinus

34
Q

% People mobile gallbladder

A

4