Weird and Wonderful Disease States Flashcards

1
Q

What is a febrile seizure?

A

seizures occurring in children aged 6 months to 5 years with a temperature greater than or equal to 38 C
-no signs of CNS infection or metabolic disturbance
-no history of afebrile seizure

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2
Q

Why do febrile seizures occur?

A

exact mechanism is unknown

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3
Q

Is recurrence of febrile seizures common?

A

recurrence after a first febrile seizure is common
-risk of epilepsy is not increased after a first simple febrile seizure

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4
Q

What are some potential risk factors for febrile seizures?

A

family history of febrile seizure
developmental delay
viral illness

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5
Q

What is the diagnosis of a febrile seizure?

A

suspected in children within the age range who are previously healthy with seizure and fever
diagnostic criteria:
-generalized tonic clonic activity with no focal compartment
-duration less than 15 minutes
-occurs no more than once in 24h
-no previous neurologic problems

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6
Q

How should febrile seizures be managed?

A

stabilization and monitoring
-do not put anything in their mouths
-try to roll onto their side or roll head to one side
-if longer than 3 minutes call ambulance
children should be reviewed by physician after a febrile seizure
most febrile seizures will have stopped before presentation to a HCP

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7
Q

Can febrile seizures be prevented?

A

no
anticonvulsants (continuous or intermittent) for single or recurrent febrile seizures not recommended
antipyretics do not affect illness course or neurologic complications

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8
Q

What are some potential causes of congenital heart disorder?

A

environmental
-maternal diabetes, teratogen exposure, alcohol, infection
genetics

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9
Q

What are the complications of congenital heart disorder?

A

pulmonary HTN
heart failure
death

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10
Q

What are the common congenital heart defects?

A

atrial septal defect
-hole in septum, O2 rich blood leaks into O2 poor blood
-peripheral consequences
coarctation of the aorta
-narrowing of aorta
-inefficient carrying of blood to body, increased BP, damage
hypoplastic left heart syndrome
-treated with surgery

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11
Q

What is the management for congenital heart defects?

A

surgery (#1)
pharmacological:
-diuretics (kids sensitive to fluid changes)
-ASA (one of the cases youll see it, go for chewable tabs)
-anticoag (enoxaparin, warfarin in older children)
-BP meds
-pulmonary HTN: sildenafil, tadalafil, bosentan

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12
Q

What is common in healthy infants?

A

reflux
-usually benign

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13
Q

When does GERD become an issue with kids?

A

interfering with daily activities or causes complications
-affecting growth

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14
Q

Describe the pathophysiology of GERD in infants.

A

they spend a lot of time lying down
frequent, liquid meals
short esophagus and LES

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15
Q

What is the main barrier to reflux?

A

LES
-relaxation is triggered by gastric distention
-relaxation continues into childhood but growth and upright positioning decrease reflux frequency

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16
Q

What are the symptoms of GERD?

A

challenging because non-specific
-over diagnosed and overtreated
crying, fussing, back arching
poor weight gain

17
Q

What is the non-pharm treatment for GERD in paeds?

A

thickened feeds
-use a thickening agent (rice starch, cereal)
-helps decrease regurgitation and increase weight gain
-commercial thickened formula
cows milk protein
-allergy may present as GERD sx
-should improve within 2 wks of avoiding cows milk
infant positioning
-while awake, post-prandial
-head elevation after feeding, supine for sleeping
-left side down positioning

18
Q

What is the evidence for H2RAs in infants?

A

data supporting efficacy in infants is limited
unsure if it improves crying or fussiness when compared to placebo

19
Q

What is the evidence for PPIs in infants?

A

decreases acid secretion but unclear if decreases symptoms

20
Q

What is the suggestion from Choosing Wisely Canada regarding acid-suppressive therapy in infants?

A

therapies should not be routinely used for treatment for otherwise well infants

21
Q

What are the adverse effects of acid suppression in infants?

A

increased risk of pulmonary and GI infections
increased risk of fractures
dose and duration dependent