Weight Loss Flashcards

1
Q

Drugs that can cause weight gain

A
  • Antipsychotics (e.g., clozapine, olanzapine, risperidone, quetiapine)
  • Diabetes drugs (insulin, sulfonylureas, meglitinides, thiazolidinediones)
  • Divalproex/valproic acid
  • Gabapentin, pregabalin
  • Lithium
  • Mirtazapine
  • Steroids
  • TCAs (e.g., amtriptyline, nortriptyline)
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2
Q

Conditions that can cause weight gain

A

Hypothyroidism

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3
Q

Drugs that can cause weight loss

A
  • ADHD drugs (e.g., amphetamine, methylphenidate)
  • Bupropion
  • GLP-1 agonists (e.g., exenatide, liraglutide)
  • Pramlintide
  • Roflumilast
  • SGLT2i (e.g., canagliflozin, empagliflozin)
  • Topiramate
  • Tirzepatide
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4
Q

Conditions that can cause weight loss

A
  • Hyperthyroidism
  • Celiac disease
  • IBD
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5
Q

Prescription weight loss drugs are indicated in

A
  • patients with a BMI ≥ 30
  • patients with a BMI ≥ 27 with at least one weight-related conditions, such as dyslipidemia, hypertension or diabetes
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6
Q

Weight loss drugs should be discontinued if

A

they don’t produce at least 5% weight loss at 12 weeks

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7
Q

All prescription weight loss drugs are contraindicated in

A

pregnancy

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8
Q

Avoid naltrexone/bupropion (Contrave) in patients with

A
  • Hypertension
  • Depression
  • Seizures
  • Taking opioids
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9
Q

Avoid use phentermine/topiramate ER (Qsymia) in patients with

A
  • Hypertension
  • Seizures
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10
Q

What supplements should be recommended to patients taking orlistat?

A
  • Multivitamin w/ A, D, E, K and beta carotene
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