Weight and Obesity Flashcards
Explain basal metabolic rate (BMR)
body’s base rate of energy usage, influenced by heredity, age, activity level, and body composition
Explain the set point hypothesis
- set point of individuals weight thermostat
- below this weight = increase in hunger and lowered metabolic rate may act to restore lost weight
What are fat cells? some key components?
adipocytes: collapsible cells that store fat
- fat-cell hyperplasia - fat cells divide when reach full capacity
- once fat cells increase, they NEVER decrease
- healthy: 25-30 billion
- Obese: 200 billion
- fat becomes endocrine (hormonal tissue)
In appetite regulation, explain the function of the lateral hypothalamus (LH)
- stimulation leads to hunger
- lesioning leads to self-starvation
In appetite regulation, explain the function of the ventromedial hypothalamus (VMH)
- lesioning leads to hunger
- stimulation causes animals to stop eating
In appetite regulation, explain the function of the circulatory system: hunger/satiety(fullness)
- hunger rises and falls with levels of glucose and insulin
- links to the number of fat cells
In appetite regulation, explain insulin
- comes from the pancreas
- helps convert glucose into fat; increase cues hunger
In appetite regulation, explain ghrelin
- comes from the stomach
- appetite stimulant
In appetite regulation, explain cholecystokinin (CCK)
- comes form the intestine
- satiety (fullness) hormones
In appetite regulation, explain PYY
appetite suppressant
Explain the longer-term weight regulation with the mice study
- mice with low leptin became obese (had uncontrollable hunger)
- leptin usually increases with body fat to produce fat cells
- leptin-obesity connection: leptin receptors less sensitive in obese people, are people producing more leptin to compensate?
Where are the most receptors for leptin?
neurons in the arcuate nucleus (ARC) of the hypothalamus; master center for short/long term weight regulation
Explain the difference between bad and good fats
bad fats
- transfats (hydrogen added to vegetable oil)
- saturated fat (no double bond)
good
- monounsaturated fat
- polyunsaturated fat
explain easy and slow burn
easy - body expends only 3 calories to turn 100 calories of fat into body fat
slower - body expends 25 calories to turn 100 calories of carbohydrate into body fat
- westerners eat about 40-45 calories from just fats
explain serum cholesterol
waxy substance essential for strong cell walls and myelination found in lipoproteins
- triglycerides
- low-density lipoproteins (LDL) - linked to heart disease
- high-density lipoproteins (HDL) - may offer some protection against heart disease
Healthy Levels
total serum below 200 of blood
- LDL/triglycerides - below 100 in blood each
- HDL - above 40 of blood
What is a good predictor of heart disease
LDL; low-density lipoproteins