weeks 5 and 6 Chronic/Patho Mobility & Oxygenation/ perfusion 1 Flashcards
Multiple sclerosis what symptoms would be likely see
- balance issues/gait changes -weakness -fatique -pain -numbness -bowel and bladder issues -impaired communications - speech issues - eye changes (diplopia = double disions)
- swallowing issues
This is a demyelinating disease of the CNS
Ataxia
poor coordination and unsteadiness
Is daily exercise good for individuals with MS
yes, but with frequent rest periods so body temperature doesn’t raise which would worsen symptoms
stress can also worsen the symptoms
Someone who has MS is typically on Interferon, what should we educate the client on while taking that drug
- wearing sunscreen
- rotation of IV site
- common side effects will mimic flu-like symptoms
how much exercise should someone get with osteoporosis?
Regular weight bearing exercises 20- 30 min a day
weight training stimulates bone mineral density
T/ F antiacids have calcium in them
true
what would someone with osteoporosis take for pharm treatments?
- calcium and vitamin D
- Bisphosphonates
- Calcitonin
- Estrogen agonists/ .antagonists SERMS
- parathyroid hormone
- receptor activator of nuclear factor Kappa- B ligand inhibitor
What should we not take with bisphosphonates?
calcium supplements or antacids that calcium are in them
Estrogen promotes bone health T/F
True
what are some medications that promote bone loss?
Corticosteroids, antiseizure, heparin, thyroid hormone
Little Vitamin D can be a risk factor for what disease?
Multiable sclerosis and osteoporosis
MS also has high relevance with people in temperature extremes, woman, some infections such as epstein bar, diabetes mellitus type 1, thyroid disease and IBS, emotional trauma and pregnancy
What is activated when someone has MS?
they will have HLA-DR2 which is present when the T-cells are activated
Too many T cells in people with MS causing Meylin breakdown
What will we see on the white matter with MS?
hard sharp sclerotic plaques
Stage 1 is inflammation
Stage 2 is plaque formation (gliosis) and demyelination
how is MS diagnosied?
Disease of exclusion
- requires 2 or more neurologic attacks
- MRI reveals MS plaque or scarring
- Evoked potential - reveal slow conduction of nerve impulses
- elvation of IgG and the presence of oligoclonal band in 90-95% of patients with MS (immune system abonrmality)
Treatments of MS?
goal is to delay the progression.
reduce autoimmune response- interferon beta 1b
reduce spasity dantrolene
anticonvulsants for parathesias
speech and vision therapy
stretching and ROM
Adaptive equipment
PT
There are 4 kinds of MS what is the most common
Relapsing-Remitting
clears relapses with stable between relapses
what are the risk factors of osteoporosis?
White or Asian, small bone structure, low body weight, post-menopausal (estrogen diffident) advanced age family history -high protein diet -people on antacids because it interferes with calcium absorption
what drugs and diseases are risk factors for Osteoporosis?
- Cushing disease
- celiac disease
- diabetes mellitus
- anorexia Nervosa
- hyper thyroid
- RA
Drugs; aluminum-containing antacids
- anticonvulsants
- heparin
- corticosteroids
Surgical: gastrectomy
what do we do to measure bone density? what test?
DEXA scan
what is the main difference between rheumatoid arthritis and osteoarthritis?
Rheumatoid has inflammation and Osteo does not.
osteoarthritis: has loss of hyaline cartilage of joints on articular surfaces, “early morning stiffness”
Rheumatoid arthritis: systematic autoimmune
Rheumatoid factor combines with IgG forming immune complex causing inflammation of synovial membranes
, Muscle atrophy decreased joint mobility
What kinds of tests and treatments can be done for osteoarthritis?
Bone Scan
- CT
- MRI
- X-ray
Treatments: rest and joint protection
heat and cold application
-nutritional therapy and exercise
- joint replacement
What kinds of tests and treatments can be done for Rheumatoid Arthritis?
- Rheumatoid factor
- Erythrocyte sedimentation rate (ESR)
- OTher inflammatory markers (CRP)
- Xrays
Treatment: PT
Occupational therapy
-joint replacement
what can we find that is similar with RA and MS?
similarities of T cells and tumor necrosis factor (TNF) in both disease
Basilar and vertebral stroke
cerebellum and brain stem
balance issues, vertigo, dysphagia, dysphonia, visual issues