week13 Flashcards
1
Q
What are antagonist?
A
a receptor is a Type of ligand or drug that dose not provoke a biological response - but blocks an agonist
affinity but NO efficacy
2
Q
What isa physiogiccals antagonist
A
substances which have opposing physiological actions but acts at a different receptor
in this histamines lower arterial pressure through Vasodilation at H1 receptor while adrenaline raises the abual pressure
3
Q
what is competitive antagonist
A
these block agonists binding
bind at the same site as agonist
antagonist reversibility bunds to receptorsat al the same binding site as endogenous Ligand- but not activating a receptor
