week 8 (population genetics) Flashcards
explain: HW equil.
- random mating and absence of evol. change leads to stable allele freq. in pop.
- calculates expected geno and allele freq. when no evolution
p^2 + 2pq + q^2 = 1
name: assumptions of HW (6)
- pop size is infinite
- random mating
- no nat. sel.
- no migration/gene flow
- no mutations
- no genetic drift
name: predictions of HW (4)
- allele freq. = stable over time
- allele distribution into genotypes is predictable
- stable equil. freq. of alleles and geno are maintained
- evol. and non-random mating effects are predictable
explain: relative fitness (w) and selection coefficient
- quantifies nat. sel.
- w = 1 means highest reproductive success for a certain trait
- indiv that rep. less -> fitness decreased by selection coefficient (s)
explain: balancing sleection
- het. geno. favoured
- alleles reach stable equil.
- selective psi acts against homo. geno.
name: factors influencing geno. and allele freq. (5)
- selection
- mutation
- gene flow
- genetic drift
- inbreeding
name: fundamentals of speciation (3)
- species concept
- reproductive isolation
- modes of speciation
question: forward mutation rate vs reverse?
- forward (mu) = rate of creating new alleles
- reverse (v) = rate of mutation to OG allele
define: gene flow
- mvt. of org. and genes between populations
- can:
⤷ introduce new alleles
⤷ increase or decrease freq. of existing alleles
define: genetic drift
- chance fluctuations of allele freq. due to sampling bias
⤷ small changes that occur randomly over time - especially prominent in small populations
explain: inbreeding
- mating between related indiv.
- increases homo. genotypes
- can lead to genotype fixation
explain: biological species concept
- group of org. are capable of interbreeding w/ each other but isolated from other species
name + explain: modes of speciation (3)
-
allopatric
- populations diverge due to physical barriers
- new sp. dev. in separate geo. locations -
sympatric
- populations share a territory
- isolated by genetic, behavioural, temporal, or other barriers
- prevents gene flow
- can have allopatric first, and then sympatric when they come back in contact -
hybrid
- formation of new sp. due to new hybridization between existing sp.
explain: hawaiian drosophila sp.
- relationships of hawaiian sp. consistent w/ geological evidence of island formation
- colonizing new islands = allopatric sp.tion
concept = founder effect
- small population enters into isolated territory
- genetic drift and inbreeding can lead to changes in alleles freq.
name (compare): mechanisms of reproductive isolation (2)
-
prezygotic = prevents indiv. from 2 diff. pop./sp. from mating
- behavioural, gametic, geographic, habitat, mechanical, temporal isolations -
postzygotic = mem. of 2 pop. can mate but non viable embyro
- hybrid breakdown, inviability, and sterility
explain: kill all hybrids design
- kept two envrt. for two sp. across 6 generations
⤷ sympatric bottles = mixed males and females of two sp.
⤷ allopatric bottles = males and females of one sp. - counted progeny in sym. bottles
⤷ counted and discarded hybrids
⤷ counted parental offspring and used them to make next gen. - killing hybrids lead to strong selection against interspecies breeding
- shows how social beha. has implications on how pop. reproductively isolate