Week 8 Medications for Endocrine Flashcards
Pituitary drug example
Desmopressin
What is the purpose of desmopressin and how does it work?
Desmopressin manages nocturnal enuresis and it manages diabetes insipidus (large urinary output) by decreasing urinary output and thirst
Adrenal Meds examples
*Glucocorticoids
*Betamethasone
*Budesonide
*Hydrocortisone
*Triamcinolone
*Methlyprednisone
*Prednisone
what are adrenal meds typically used for?
short term tx of inflammatory diseases
Topical adrenal med examples and indication
Topical (Rash- dermatitis -
Triamcinolone, hydrocortisone),
-for little areas
-CAN OD
inhaled/nasal adrenal meds indication and examples
Inhaled/nasal (allergies & Asthma & COPD -
Rhinocort, Pulmicort, Flovent),
-respiratory
injection adrenal meds indication and example
Injection (PN, asthma, COPD-
Methylprednisolone)
oral/systemic adrenal med examples
Oral/systemic (Arthritis, systemic lupus, allergic reactions-prednisone)- long term
what are all the SE and AE of adrenal meds
Delayed wound healing (especially in long term use)
Immunosuppression (immunosuppressant effect)
Risk of peptic ulcers
Rebound affect
Increases blood glucose (not inherently a contraindication of diabetes)
Weight gain (messes with adrenal gland and fluid retention like in cushin’s, the overproduction of the steroid is causing weight gain)
Growth issues in kids, stunted
Insomnia (give AM) will impact the circadian rhythm
Neves, shakiness (restless)
Osteoporosis
Causes thinning of the skin with topical shorter term
reprised what are the SE AE of adrenal meds?
It causes restlessness (shakes, nerves, insomnia)
Causes growth issues including weight because they are steroids
Cushins and water retnetion
Skin irritation with topical uses
Weakens the immune system: nonhealing wounds, peptic ulcers, immunosuppression, infection
Osteoporosis
What is a severe complication of adrenal meds
Adrenal crisis if stopped suddenly due to sudden drop in serum cortisone levels
the adrenal glands of the kidneys will stop production of cortisone levels due to the decreased production
what are the symptoms of adrenal meds?
hyponatremia, hypotension,
loss of consciousness, death
what is a caution of adrenal meds?
diabetes because it can increase sugar levels
what is hypothyroid treated with
levothyroxine
by replacing hormones the thyroid cant produce.
what are the nursing implications of thyroxine?
Take it with water in the mornings on an empty stomach
(about 1 hr before eating)
Make sure not to take it with other meds to avoid interactions
Monitor for adverse effects like tachy, HTN, anxiety (HYPER)
DONT switch brands
safe for pregnancy
it can take 5-8 weeks to regulate
Adrenal meds med administration
make sure to taper prednisone to avoid adrenal crisis
give with food to avoid GI upset
give in the AM
avoid grapefruit juice (increases effect)
infection prevention (immunosupression)
Adrenal meds implications
assess renal disease (affects kidneys)
weight/height (cushins, and stunted growth)
glucose (increases blood sugar)
electrolytes (symptoms of adrenal crisis)
Antithyroid agents
Radioactive iodine 131
-1 dose?
Propylthiouracil PTU
long term
Indication radioactive iodine
Hyperthyroidism
Acute thyrotoxicosis
Graves disease
what is the nursing implication of radioactive iodine
used for candidates who are not eligible candidates
radioactive iodine SE AE
metallic taste
swollen gums and sore teeth
what is the indication for propylthiouracil PTU
hyperthyroidism
Graves
Emergency treatment
Thyrotoxicosis
SEAE of propyliouracil
long term use can become too much causes hypothyroidism
hepatitis
Nursing implication of propylthiouracil
will not cure bulging eyes
parathyroid meds
bisposphonates
calcitonins
bisphosphonates indication
slow normal and abnormal bone resorption