Week 8 Medications for Endocrine Flashcards

1
Q

Pituitary drug example

A

Desmopressin

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2
Q

What is the purpose of desmopressin and how does it work?

A

Desmopressin manages nocturnal enuresis and it manages diabetes insipidus (large urinary output) by decreasing urinary output and thirst

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3
Q

Adrenal Meds examples

A

*Glucocorticoids
*Betamethasone
*Budesonide
*Hydrocortisone
*Triamcinolone
*Methlyprednisone
*Prednisone

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4
Q

what are adrenal meds typically used for?

A

short term tx of inflammatory diseases

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5
Q

Topical adrenal med examples and indication

A

Topical (Rash- dermatitis -
Triamcinolone, hydrocortisone),
-for little areas
-CAN OD

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6
Q

inhaled/nasal adrenal meds indication and examples

A

Inhaled/nasal (allergies & Asthma & COPD -
Rhinocort, Pulmicort, Flovent),
-respiratory

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7
Q

injection adrenal meds indication and example

A

Injection (PN, asthma, COPD-
Methylprednisolone)

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8
Q

oral/systemic adrenal med examples

A

Oral/systemic (Arthritis, systemic lupus, allergic reactions-prednisone)- long term

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9
Q

what are all the SE and AE of adrenal meds

A

Delayed wound healing (especially in long term use)
Immunosuppression (immunosuppressant effect)
Risk of peptic ulcers
Rebound affect
Increases blood glucose (not inherently a contraindication of diabetes)
Weight gain (messes with adrenal gland and fluid retention like in cushin’s, the overproduction of the steroid is causing weight gain)
Growth issues in kids, stunted
Insomnia (give AM) will impact the circadian rhythm
Neves, shakiness (restless)
Osteoporosis
Causes thinning of the skin with topical shorter term

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10
Q

reprised what are the SE AE of adrenal meds?

A

It causes restlessness (shakes, nerves, insomnia)
Causes growth issues including weight because they are steroids
Cushins and water retnetion
Skin irritation with topical uses
Weakens the immune system: nonhealing wounds, peptic ulcers, immunosuppression, infection
Osteoporosis

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11
Q

What is a severe complication of adrenal meds

A

Adrenal crisis if stopped suddenly due to sudden drop in serum cortisone levels
the adrenal glands of the kidneys will stop production of cortisone levels due to the decreased production

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12
Q

what are the symptoms of adrenal meds?

A

hyponatremia, hypotension,
loss of consciousness, death

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13
Q

what is a caution of adrenal meds?

A

diabetes because it can increase sugar levels

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14
Q

what is hypothyroid treated with

A

levothyroxine
by replacing hormones the thyroid cant produce.

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15
Q

what are the nursing implications of thyroxine?

A

Take it with water in the mornings on an empty stomach
(about 1 hr before eating)
Make sure not to take it with other meds to avoid interactions
Monitor for adverse effects like tachy, HTN, anxiety (HYPER)
DONT switch brands
safe for pregnancy
it can take 5-8 weeks to regulate

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16
Q

Adrenal meds med administration

A

make sure to taper prednisone to avoid adrenal crisis
give with food to avoid GI upset
give in the AM
avoid grapefruit juice (increases effect)
infection prevention (immunosupression)

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17
Q

Adrenal meds implications

A

assess renal disease (affects kidneys)
weight/height (cushins, and stunted growth)
glucose (increases blood sugar)
electrolytes (symptoms of adrenal crisis)

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18
Q

Antithyroid agents

A

Radioactive iodine 131
-1 dose?

Propylthiouracil PTU
long term

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19
Q

Indication radioactive iodine

A

Hyperthyroidism
Acute thyrotoxicosis
Graves disease

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20
Q

what is the nursing implication of radioactive iodine

A

used for candidates who are not eligible candidates

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21
Q

radioactive iodine SE AE

A

metallic taste
swollen gums and sore teeth

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22
Q

what is the indication for propylthiouracil PTU

A

hyperthyroidism
Graves
Emergency treatment
Thyrotoxicosis

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23
Q

SEAE of propyliouracil

A

long term use can become too much causes hypothyroidism
hepatitis

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24
Q

Nursing implication of propylthiouracil

A

will not cure bulging eyes

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25
Q

parathyroid meds

A

bisposphonates
calcitonins

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26
Q

bisphosphonates indication

A

slow normal and abnormal bone resorption

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27
Q

bisphosphonates SE AE

A

osteonecrosis of the jaw
ocular inflammation
esophagitis
bone pain

28
Q

bisphosphonate nsg implication

A

ability to sit up 30 mins!

29
Q

Calcitonin’s indication and SE AE

A

stops bone reabsorption
(decrease ca levels)

30
Q

calcitonin SE AE

A

flushed face and hands
nasal spray will cause irritation and bleeding

31
Q

Rapid acting insulin example

A

Lispro (humolog)
Aspart (novolog)

32
Q

Onset and peak of rapid acting insulin
Lispro and Aspart

A

onset 5-15min
peak 1-2 hrs

33
Q

Short Acting Insulin example

A

Regular (humulin)

34
Q

onset and peak of regular (Humulin)

A

takes longer than rapid
30-60min
2.5h peak

35
Q

route of regular insulin

A

SQ IV
REGULAR is the ONLY insulin that is IV!!!

36
Q

intermediate-acting
example
onset
peak

A

NPH
1-2 hour onset
4-8 hr peak

37
Q

Long acting insulin examples

A

glargine (Lantus)
detemir (Levemir)

38
Q

glargine
detemir
onset
peak

A

1-2 hrs
no peak
duration: 24 hrs

39
Q

Combination insulins:

A

Humulin 70/30 or
Novolin 70/30 NPH and Rapid

40
Q

indication of antidiabetic treatments

A

diabetes
severe hyperkalemia

41
Q

SE AE of antidiabetic medication INUSULINs

A

hypoglycemia
lipohypertrophy

42
Q

Nursing implications of insulin

A

check the blood glucose levels
evaluate A/C

43
Q

what should nurses know about insulins

A

ensure food is available for rapid and short acting insulins
long acting insulin dosing is daily or every 12 hours
Long acting CANNOT be mixed with other types of insulin

44
Q

med admin insulin

A

rotating sites
adjusting dose for pt with infections
spike w food
clear then cloudy
pumps are rapid or short acting only (for control)

45
Q

storage of insulin

A

unopened can be in the fridge til expiration
room temp insulins can be used for 1month max

46
Q

oral antidiabetic treatments ex

A

metformin

47
Q

metformin indication

A

Diabetes type II
polycystic ovarian syndrome
metabolic syndrome (due to insulin resistance)

48
Q

SEAE of metformin

A

Nausea and Diarrhea

49
Q

Interactions with metformin

A

alcohol

50
Q

why does ETOH intereact w/ metformin?

A

it inhibits breakdown of lactic acid which can intensify lactic acidosis
to counteract lactic acidosis the body will begin to breath out rapidly
iodine containing contrasts for CT

51
Q

nursing implications for metformin

A

tapper up the dose to decrease GI issues
take it with food
hold the med for 48 hours if they will have a CT scan and avoid 48 hours after
hard on the kidneys
-may need to elimiate other nephrotoxic drugs

52
Q

what should a nurse monitor for a patient on metformin

A

CREATINE

53
Q

Sulfonylureas
examples

A

Glimepiride
Glipizide
Glyburide

54
Q

Sulfonylureas indication

A

for type II diabetes
-oral will never be used for type I

55
Q

SE AE of sulfonylureas

A

hypoglycemia
weight gain
heartburn

56
Q

Interactions

A

beta blockers, alcohol

57
Q

nursing implications of sulfonyulureas

A

take in the morning
30 mins before breakfast

58
Q

piolitazone indication

Thizolidnediones

A

Diabetes melluitis type II

59
Q

pigolitazone SE AE

A

moderate weight gain
edema
mild anemia
hepatic toxicity

60
Q

nsg implication of pioglitazone

A

2011 actos causes bladder cancer lawsuit
still used in US
not in other coutnries

61
Q

Dipeptidyle peptidoase IV inhibitors

A

Sitagliptin

62
Q

sitagliptin is used to treat

A

type II diabetes
either on its own or with metformin
sulfonylurea
but not with INSULIN

63
Q

SE AE of sitagliptin SE AE

A

upper respiratory tract infections
headache
diarrhea

64
Q

nsg implication of sitagliptin

A

hypoglycemia cann occur especiialy if it is used with sulfonylurea

65
Q

Glucose elevating med examples

A

Glucagon
50% dextrose in water
concentrated glucose PO
-chewable tablets, gels

66
Q

nsg implication of

A

assess blood glucose before administering glucagon ‘
higher levels of glucoagon are typically not harmful
asses pt ability to swallow

67
Q

pt education of blood raising meds

A

keep glucose with you at all times