Week 7 Histophathology Nervous Tissue Flashcards
What is this an image of? What is pointed at by the green and blue arrow?
Cerebral Cortex
Green: glial cell
Blue: Pyramidal neuron
Identify the location of the two types of matter
This is the CNS
Gray matter: Outside
White matter: inside
What are some key points about the cerebellum?
Identifier is the Purkinje neuron
Highly convuluted
Grey matter has three layers (molecular, Purkinje, granular)
In the spinal cord, where are is the white/grey matter found?
White matter: exterior
Grey matter: interior
Identify the source of the slide. What is each arrow pointing at?
Cerebellum
Red: granular
Blue: Molecular
Green: Purkinje
Black: White matter
What is this a slide of? Where are the white/gray matter? Identify the portion of the meninges pointed at by each arrow.
The spinal cord.
Grey inside, White outside
Black: Dura mater
Blue: Arachnoid
Green: Pia mater
What is the easiest what to orient yourself when looking at a slide of the spinal chord?
Look at the horns of the grey mater. The dorsal hords will touch the edge while the ventral horns are rounded and don’t reach the edge.
What is the Nissl substance?
Abundant rough ER
What are ependymal cells and where are they found?
Low columnar epithelial cells found lining the central canal and ventricles of the brain
What are the largest and easiest spinal neurons to recognize? Where are they found?
Motoneurons
What is the large cell in the center? What cells are surrounding the outside? Where are they found?
pseudo-unipolar sensory neurons; satellite cells; Dorsal root ganglia
Sensory neurons in the DRG are the best example of what type of cell?
pseudounipolar neurons
What is responsible for the wagon wheel appearance of these cells? Where are they found?
Protein that was previously supporting myelin - peripheral nerve
What are the four types of glial cells?
Astrocytes, Schwann cells, Microglia, Oligodendrocytes (olgiodendroglia)
Which glial cells is responsible for inducing the BBB?
Astrocytes
What are the differences b/t oligiodendrocyts and schwann cells?
Oligodendrocytes: CNS, multiple myelin segment
Schwann: PNS, one myelin segment
Name the type of tissue from left to right.
Peripherial nervous, Tendon, Smooth muscle
What are the definine cells of the grey matter in the spinal cord?
Large multipolar nerve cells (Horn Cells)
What is the role of ependymal cells?
These cells line the central canal of the spinal cord and ventricles of the brain and are ciliated in some cases to promote movement of CSF
What does Nissl Substance help identify in the spinal cord?
Motor neurons
What are the distinguishing features of the dorsal root ganglia?
Large round cell bodies with pseudounipolar sensory neurons that are surrounded by satellite cells or glia cells
What are the three layers of covering in the peripherial nerve?
Epineurium, perineurium, and endoneurium
What do schwann cells do?
These myelinate single neurons in the periphery
What are the four parts of the meninges?
Dura Mater - Outer most
Arachnoid - thin layer above sub arachnoid
Subarachnoid space - contains the CSF
Pia mater - adheres to surface of spinal cord
What is the role of microglia?
Macrophages of the brain these phagocytose material
What is different about the oligodendrocyte and schwann cell in regards to their location?
The schawnn cell is located in the periphery and the oligodendrocyte is in the CNS
What is this a picture of?
Astrocytes - note the star shape
What is this a picture of?
Axonal Nerve -Transverse section
What is this a picture of? What the little hand is on top of?
Endoneurium
What is this a picture of?
This is a longitudinal section of a peripherial nerve
What is this a picture of? Most specifically where the stain is not showing up? And what is this stain staining?
It is a peripherial nerve; what is not being stained is the Node of Ranvier and the stain is staining for Myelin
What is the black arrow pointing at?
Perineurium
