Week 7 (Exam 3) Flashcards
Diagnose catatonic type schizophrenia
At least 2: Motoric immobility (catalepsy or stupor) Excessive motor activity Excessive negativism or mutism Peculiarity of movements Echolalia or echopyrexia
DM psychiatric sx
Frustration, loneliness, dejection, depression
Operant conditioning vs classical conditioning
Classical: Together in time
Operant: sequential
Panic attack
Peaks within 10 minutes, pick at least 4:
Palpitations, sweating, trembling, SOB, CP, Lightheadedness, Fear of losing control, Paresthesias, chills or hot flashes
Toxicities causing confusions
Vitamin A and D, Iron
Psychiatric effects of corticosteroids
Mania, psychosis (hallucinations)
OCD vs OCPD
PD don’t perceive they have a problem
Thiamine deficiency physical and psychiatric sx
Wernicke-Korsakoff, neuropathy, malaise, alcoholism
Poor concentration, confusion, confabulation
TCA side effects
Cholinergic: dry mouth, constipation
Panic disorder criteria
Recurrent unexpected panic attacks AND at least one attack followed by 1 month+ of persistent concern about additional attacks, worry about the implications of the attacks or its consequences, and/or significant change in behavior related to the attacks
Toxicities causing cognitive dysfuncion
Lead
Treat EPS (non-terdive dyskinesia)
Anticholinergics (Benztropine, Trihyxyphenidyl)
Anti-Histamine (Diphenhydramine)
GAD criteria
More days than not, most of the day, 6+ months
Pick 3: Restlessness, easily fatigued, difficulty concentration, irritability, muscle tension, sleep disturbance
Psychiatric Sx of SLE
Depression, mood disturbances
Psychosis!, delusions, hallucinations
Hypomanic episode
Less severe than manic and only 4 days
So psychotic features, social/occupational impairment
Major side effect associated with treating schizophrenia with Clozapine
Agranulocytosis
Psychiatric sx of acute intermittent porphyria
acute depression, agitation, paranoia, visual hallucinations
Anti-depressant side effects
Mania (in bipolar patients), anxiety, insomnia
Major side effect of treating schizophrenmia with Ziprasidone
QTc Prolongation
Treat Acute Psychosis (schizophrenia associated)
IM Haloperidol, Fluphenazine
Lorazepam
Treat Tardive Dyskinesia
Benztropine, Deuterabenazine
Cobalamin deficiency physical and psychiatric sx
Pallor, dizziness, neuropathy, ataxia
Irritability, inattentiveness, psychosis, dementia
Treat anything below 400
Delusional Disorder
Delusions for at least 1 month
Never met Criterion A for Schizophrenia
Diagnose Schizophrenia
6 mos of 2+ of: Delusions, Hallucinations, Disorganized Speech, Disorganized/Catatonic behavior, negative sx
1 month of cluster A sx
Chron’s disease pre-existing condition
Often panic disorder
UC is dependent personalities, maybe
Schizophreniform
Meets criteria A, D, and E for schizophrenia
At least 1 month, shorter than 6 months
MS psychiatric sx
Anxiety, euphoria, mania
What adverse effects are associated with treating schizophrenia with first generation anti-psychotics?
Extrapyramidal: Acute Dystonic Reactions, Drug-induced PD, Akathisia, Antipsychotic-induced catatonia, tardive dyskinesia
Neuroleptic Malignant Syndrome
Treatments for Bipolar disorders
1: Mood stabilizers (lithium, valproic acid)
Also carbamazepine, 2nd gen anti-psychs, lamatrogine
Hyponatremia physical and psychiatric sx
Excessive thirst, polydipsia, stupor, coma, seizures
Confusion / delirium, lethargy, personality changes
Psychiatric sx of Hyperthyroidism
Nervousness, excitability, irritability, pressured speech, insomnia, psychosis, visual hallucination
Neurotransmitters of major depressive disorder
Lower b-adrenergics, abnormal NE function
Decreased DA
Decreased 5HT
Decreased GABA
Criteria for a manic episode
At least 1 week, pick 3:
Inflated self esteem/grandiosity, decreased need for sleep, more talkative, racing thoughts, distractibility, more goal-oriented behavior, excessive pleasure-seeking
Brief Psychotic Disorder
At least 2 of:
Delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior
Episode at least 1 day, less than 1 month
Eventual return to premorbid functioning
Criteria for Major depressive disorder
1+ major depressive episodes and absence of any manic, hypomanic, or mixed episodes
Persistent depressive disorder criteria
Depressed mood most of the day for at least 2 years
Cant go more than 2 months without sx
Not severe enough to qualify as major depressive episode
Toxicities causing Psychosis
Copper
Reduce suicide in schizophrenia patients
Clozapine
Psychiatric sx of Hypothyroidism
Lethargy, depression, personality change, paranoia
Psychiatric sx of frontal lobe tumor
Mood changes, irritability, facetiousness, impaired judgement, impaired memory, delirium, loss of speech, loss of smell
Physical and psychiatric sx of hepatic encephalopathy
Asterixis, hyperreflexia, spider angioma, palmar erythema, ecchymosis, liver enlargement/atrophy
Euphoria, disinhibition, psychosis, depression
Cyclothymic disorder
Dysthmyic disorder with intermittent hypomanic periods
2 years of repeated hypomania, depressive episodes
(no major depressive manic or mixed for 1st 2 years)
PTSD tx
SSRIs, Cognitive Processing Therapy (support groups and eye movement desensitization and reprocessing [EMDR])
Bipolar I vs II
I: At least 1 manic or mixed episode
II: At least 1 major depressive and 1 hypomanic episode
Toxicities affecting peripheral nerve fxn
B6 and B12
Schizoaffective Disorder
Uninterrupted period of illness with either major depressive or manic episode w/ sx that meet criterion A for schizophrenia
Same period of illness, delusions / hallucinations at least 2 weeks without prominent mood sx
Pancreatic cancer psychiatric sx
weight loss, abdominal pain, depression, lethargy, anhedonia, apathy, decreased energy
Criteria for major depressive episode
2 weeks
Depressed mood and loss of interest/pleasure
Pick 3 more: loss of energy, inability to concentrate, thoughts of death or suicide, psychomotor agitation, insomnia, weight loss or gain, feelings of worthlessness or guilt, etc
NT responses to stress
Increased Catecholamines
Increased 5HT (+potentiating glucocorticoids)
Corticotripin Releasing Factor triggers ACTH
Psychiatric side effects of glucocorticoids
Mania, psychosis
Avoid giving these to elderly with delirium
Benzos, Benadryl/diphenhydramine